Detalles de la búsqueda
1.
On the Possible Effect of Phytic Acid (Myo-Inositol Hexaphosphoric Acid, IP6) on Cytochromes P450 and Systems of Xenobiotic Metabolism in Different Hepatic Models.
Int J Mol Sci
; 25(7)2024 Mar 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38612422
2.
Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
Drug Metab Dispos
; 46(3): 223-236, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29269410
3.
Novel role for carbohydrate responsive element binding protein in the control of ethanol metabolism and susceptibility to binge drinking.
Hepatology
; 62(4): 1086-100, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25761756
4.
In vitro infection of primary human hepatocytes by HCV-positive sera: insights on a highly relevant model.
Gut
; 63(9): 1490-500, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24153249
5.
The WNT/ß-catenin pathway is a transcriptional regulator of CYP2E1, CYP1A2, and aryl hydrocarbon receptor gene expression in primary human hepatocytes.
Mol Pharmacol
; 86(6): 624-34, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25228302
6.
Nuclear receptors in the cross-talk of drug metabolism and inflammation.
Drug Metab Rev
; 45(1): 122-44, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23330545
7.
Mitochondria Transfer from Mesenchymal Stem Cells Confers Chemoresistance to Glioblastoma Stem Cells through Metabolic Rewiring.
Cancer Res Commun
; 3(6): 1041-1056, 2023 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37377608
8.
Butyrate, a typical product of gut microbiome, affects function of the AhR gene, being a possible agent of crosstalk between gut microbiome, and hepatic drug metabolism.
J Nutr Biochem
; 107: 109042, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35533897
9.
Glucose Starvation or Pyruvate Dehydrogenase Activation Induce a Broad, ERK5-Mediated, Metabolic Remodeling Leading to Fatty Acid Oxidation.
Cells
; 11(9)2022 04 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-35563698
10.
Primary hepatocytes isolated from human and porcine donors display similar patterns of cytochrome p450 expression following exposure to prototypical activators of AhR, CAR and PXR.
Curr Res Toxicol
; 2: 149-158, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34345857
11.
Albumin is a secret factor involved in multidirectional interactions among the serotoninergic, immune and endocrine systems that supervises the mechanism of CYP1A and CYP3A regulation in the liver.
Pharmacol Ther
; 215: 107616, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-32590025
12.
Regulation of CAR and PXR Expression in Health and Disease.
Cells
; 9(11)2020 10 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-33142929
13.
Biocompatible modified water as a non-pharmaceutical approach to prevent metabolic syndrome features in obesogenic diet-fed mice.
Food Chem Toxicol
; 141: 111403, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32387306
14.
The Anti-Cancer Drug Dabrafenib Is a Potent Activator of the Human Pregnane X Receptor.
Cells
; 9(7)2020 07 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32650447
15.
Microtubules-interfering agents restrict aryl hydrocarbon receptor-mediated CYP1A2 induction in primary cultures of human hepatocytes via c-jun-N-terminal kinase and glucocorticoid receptor.
Eur J Pharmacol
; 581(3): 244-54, 2008 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-18177856
16.
Altered cytokine profile under control of the serotonergic system determines the regulation of CYP2C11 and CYP3A isoforms.
Food Chem Toxicol
; 116(Pt B): 369-378, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29698782
17.
Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding.
J Pharm Sci
; 107(7): 1957-1972, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29524447
18.
Mesenchymal stem cells seeded on a human amniotic membrane improve liver regeneration and mouse survival after extended hepatectomy.
J Tissue Eng Regen Med
; 12(4): 1062-1073, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29106037
19.
Changes in metabolism affect expression of ABC transporters through ERK5 and depending on p53 status.
Oncotarget
; 9(1): 1114-1129, 2018 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29416681
20.
Mitochondrial Complex I activity signals antioxidant response through ERK5.
Sci Rep
; 8(1): 7420, 2018 05 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29743487