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1.
Crystal Structure of Human CD47 in Complex with Engineered SIRPα.D1(N80A).
Molecules
; 27(17)2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36080360
2.
IMM47, a humanized monoclonal antibody that targets CD24, exhibits exceptional anti-tumor efficacy by blocking the CD24/Siglec-10 interaction and can be used as monotherapy or in combination with anti-PD1 antibodies for cancer immunotherapy.
Antib Ther
; 6(4): 240-252, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37846296
3.
The novel high-affinity humanized antibody IMM40H targets CD70, eliminates tumors via Fc-mediated effector functions, and interrupts CD70/CD27 signaling.
Front Oncol
; 13: 1240061, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37849799
4.
SIRPα-Fc fusion protein IMM01 exhibits dual anti-tumor activities by targeting CD47/SIRPα signal pathway via blocking the "don't eat me" signal and activating the "eat me" signal.
J Hematol Oncol
; 15(1): 167, 2022 11 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36384978
5.
IMM0306, a fusion protein of CD20 mAb with the CD47 binding domain of SIRPα, exerts excellent cancer killing efficacy by activating both macrophages and NK cells via blockade of CD47-SIRPα interaction and FcÉ£R engagement by simultaneously binding to CD47 and CD20 of B cells.
Leukemia
; 37(3): 695-698, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36575242
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