Detalles de la búsqueda
1.
Serotonin/5-HT7 receptor provides an adaptive signal to enhance pigmentation response to environmental stressors through cAMP-PKA-MAPK, Rab27a/RhoA, and PI3K/AKT signaling pathways.
FASEB J
; 37(4): e22893, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36961387
2.
Discovery and characterization of a novel cGAS covalent inhibitor for the treatment of inflammatory bowel disease.
Acta Pharmacol Sin
; 44(4): 791-800, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36229599
3.
P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib.
Acta Pharmacol Sin
; 43(2): 457-469, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-33850273
4.
Natural product 1,2,3,4,6-penta-O-galloyl-ß-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase.
Acta Pharmacol Sin
; 43(2): 470-482, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-33850276
5.
Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.
Clin Sci (Lond)
; 135(7): 925-941, 2021 04 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33786590
6.
Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents.
Bioorg Chem
; 111: 104887, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33865055
7.
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (RORγt) modulators: insights into different protein behaviors with "short" and "long" inverse agonists.
Acta Pharmacol Sin
; 42(9): 1524-1534, 2021 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-33239687
8.
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements.
Angew Chem Int Ed Engl
; 59(29): 12105-12112, 2020 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32277730
9.
Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke.
Angew Chem Int Ed Engl
; 59(6): 2429-2439, 2020 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31782597
10.
Highly diverse cembranoids from the South China Sea soft coral Sinularia scabra as a new class of potential immunosuppressive agents.
Bioorg Med Chem
; 27(15): 3469-3476, 2019 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31253536
11.
The inhibitory mechanism of aurintricarboxylic acid targeting serine/threonine phosphatase Stp1 in Staphylococcus aureus: insights from molecular dynamics simulations.
Acta Pharmacol Sin
; 40(6): 850-858, 2019 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796354
12.
The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1.
Mol Cancer
; 17(1): 63, 2018 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29466992
13.
Development of a high-throughput fluorescence polarization assay for the discovery of EZH2-EED interaction inhibitors.
Acta Pharmacol Sin
; 39(2): 302-310, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28858300
14.
Identification of small molecule inhibitors targeting the SMARCA2 bromodomain from a high-throughput screening assay.
Acta Pharmacol Sin
; 39(9): 1544-1552, 2018 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-29795359
15.
Function-Oriented Synthesis of Marine Phidianidine Derivatives as Potential PTP1B Inhibitors with Specific Selectivity.
Mar Drugs
; 16(3)2018 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-29558377
16.
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.
Molecules
; 23(3)2018 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29498708
17.
[Advances of mechanism research on procyanidin in prevention and treatment of type 2 diabetes mellitus].
Zhongguo Zhong Yao Za Zhi
; 42(20): 3866-3872, 2017 Oct.
Artículo
en Zh
| MEDLINE | ID: mdl-29243419
18.
Trimer procyanidin oligomers contribute to the protective effects of cinnamon extracts on pancreatic ß-cells in vitro.
Acta Pharmacol Sin
; 37(8): 1083-90, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-27238208
19.
Eutypenoids A-C: Novel Pimarane Diterpenoids from the Arctic Fungus Eutypella sp. D-1.
Mar Drugs
; 14(3)2016 Mar 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-26959036
20.
Syndrome Differentiation Analysis on Mars500 Data of Traditional Chinese Medicine.
ScientificWorldJournal
; 2015: 125736, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26495414