Detalles de la búsqueda
1.
Adjusting Catalytic Activity of ß-Amyrin Synthase GgBAS by Utilizing the Plasticity Residues of an Active Site.
J Chem Inf Model
; 64(9): 3933-3941, 2024 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-38666964
2.
NIMO: A Natural Product-Inspired Molecular Generative Model Based on Conditional Transformer.
Molecules
; 29(8)2024 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38675687
3.
A chemoinformatic analysis on natural glycosides with respect to biological origin and structural class.
Nat Prod Rep
; 40(9): 1464-1478, 2023 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37070562
4.
Molecular dynamic simulations identifying the mechanism of holoenzyme formation by O-GlcNAc transferase and active p38α.
Phys Chem Chem Phys
; 25(11): 8090-8102, 2023 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36876722
5.
Results of a phase 2, multicenter, single-arm, open-label study of lenalidomide in pediatric patients with relapsed or refractory acute myeloid leukemia.
Pediatr Blood Cancer
; 68(7): e28946, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33694257
6.
Accelerating the identification of subtype selective inhibitors via Three-Dimensional Biologically Relevant Spectrum (BRS-3D): The monoamine oxidase subtypes as a case study.
Bioorg Chem
; 106: 104503, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33280834
7.
Neonatal Fc Receptor (FcRn) Enhances Tissue Distribution and Prevents Excretion of nab-Paclitaxel.
Mol Pharm
; 16(6): 2385-2393, 2019 06 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31002261
8.
Novel C7-Substituted Coumarins as Selective Monoamine Oxidase Inhibitors: Discovery, Synthesis and Theoretical Simulation.
Molecules
; 24(21)2019 Nov 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31694262
9.
Different Nanoformulations Alter the Tissue Distribution of Paclitaxel, Which Aligns with Reported Distinct Efficacy and Safety Profiles.
Mol Pharm
; 15(10): 4505-4516, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30180593
10.
Phase 1b study of the mammalian target of rapamycin inhibitor sirolimus in combination with nanoparticle albumin-bound paclitaxel in patients with advanced solid tumors.
Cancer
; 121(11): 1817-26, 2015 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25649370
11.
Pharmacologic sensitivity of paclitaxel to its delivery vehicles drives distinct clinical outcomes of paclitaxel formulations.
Mol Pharm
; 12(4): 1308-17, 2015 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-25714793
12.
Combined treatment with lenalidomide and epoetin alfa in lower-risk patients with myelodysplastic syndrome.
Blood
; 120(17): 3419-24, 2012 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22936658
13.
Discovery of a SUCNR1 antagonist for potential treatment of diabetic nephropathy: In silico and in vitro studies.
Int J Biol Macromol
; 268(Pt 2): 131898, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38677680
14.
Developing TeroENZ and TeroMAP modules for the terpenome research platform TeroKit.
Database (Oxford)
; 20232023 05 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37207351
15.
Aiding early clinical drug development by elucidation of the relationship between tumor growth inhibition and survival in relapsed/refractory multiple myeloma patients.
EJHaem
; 3(3): 815-827, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-36051011
16.
Population Pharmacokinetics and Exposure-Response Analysis of nab-Paclitaxel in Pediatric Patients With Recurrent or Refractory Solid Tumors.
Clin Pharmacol Drug Dev
; 10(2): 115-130, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-32459889
17.
Predicting lung adenocarcinoma disease progression using methylation-correlated blocks and ensemble machine learning classifiers.
PeerJ
; 9: e10884, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33628643
18.
First-in-Human, Single- and Multiple-Ascending-Dose Studies in Healthy Subjects to Assess Pharmacokinetics, Pharmacodynamics, and Safety/Tolerability of Iberdomide, a Novel Cereblon E3 Ligase Modulator.
Clin Pharmacol Drug Dev
; 10(5): 471-485, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32969202
19.
Population Pharmacokinetics and Exposure-Response Relationship of Luspatercept, an Erythroid Maturation Agent, in Anemic Patients With ß-Thalassemia.
J Clin Pharmacol
; 61(1): 52-63, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32696522
20.
Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine.
J Neurochem
; 114(3): 873-85, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20492355