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1.
Fabricating and investigating a beveled mesa with a specific inclination angle to improve electrical and optical performances for GaN-based micro-light-emitting diodes.
Opt Lett
; 48(22): 5863-5866, 2023 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37966738
2.
An Unusual Benzoisoquinoline-9-one Derivative and Other Related Compounds with Antiproliferative Activity from Hawaiian Endophytic Fungus Peyronellaea sp. FT431.
Molecules
; 24(1)2019 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30621059
3.
Synthesis and Biological Evaluation of Benzimidazole Phenylhydrazone Derivatives as Antifungal Agents against Phytopathogenic Fungi.
Molecules
; 21(11)2016 Nov 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27879685
4.
Synthesis and antifungal activity of 1,2,3-triazole phenylhydrazone derivatives.
Org Biomol Chem
; 13(2): 477-86, 2015 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-25374053
5.
Discovery of IHMT-337 as a potent irreversible EZH2 inhibitor targeting CDK4 transcription for malignancies.
Signal Transduct Target Ther
; 8(1): 18, 2023 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-36642705
6.
Discovery of dihydropyridinone derivative as a covalent EZH2 degrader.
Eur J Med Chem
; 261: 115825, 2023 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37826933
7.
Enantioselective total synthesis of marine diterpenoid clavulactone.
Angew Chem Int Ed Engl
; 51(26): 6484-7, 2012 Jun 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-22644725
8.
Discovery of IHMT-EZH2-115 as a Potent and Selective Enhancer of Zeste Homolog 2 (EZH2) Inhibitor for the Treatment of B-Cell Lymphomas.
J Med Chem
; 64(20): 15170-15188, 2021 10 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34664960
9.
Discovery of (E)-N-(4-methyl-5-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thiazol-2-yl)-2-(4-methylpiperazin-1-yl)acetamide (IHMT-TRK-284) as a novel orally available type II TRK kinase inhibitor capable of overcoming multiple resistant mutants.
Eur J Med Chem
; 207: 112744, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32949955
10.
Effect of pharmaceutical care on clinical outcomes of outpatients with type 2 diabetes mellitus.
Patient Prefer Adherence
; 11: 897-903, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28507433
11.
Synthesis of 1,2,3-triazole hydrazide derivatives exhibiting anti-phytopathogenic activity.
Eur J Med Chem
; 126: 171-182, 2017 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27750151
12.
Discovery of N-(5-((5-chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)-4-methoxy-2-(4-methyl-1,4-diazepan-1-yl)phenyl)acrylamide (CHMFL-ALK/EGFR-050) as a potent ALK/EGFR dual kinase inhibitor capable of overcoming a variety of ALK/EGFR associated drug resistant mutants in NSCLC.
Eur J Med Chem
; 139: 674-697, 2017 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28850922
13.
Discovery of N-(3-(5-((3-acrylamido-4-(morpholine-4-carbonyl)phenyl)amino)-1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-2-methylphenyl)-4-(tert-butyl)benzamide (CHMFL-BTK-01) as a highly selective irreversible Bruton's tyrosine kinase (BTK) inhibitor.
Eur J Med Chem
; 131: 107-125, 2017 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28315597
14.
Structure-activity relationship investigation for benzonaphthyridinone derivatives as novel potent Bruton's tyrosine kinase (BTK) irreversible inhibitors.
Eur J Med Chem
; 137: 545-557, 2017 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28628824
15.
Irreversible inhibition of BTK kinase by a novel highly selective inhibitor CHMFL-BTK-11 suppresses inflammatory response in rheumatoid arthritis model.
Sci Rep
; 7(1): 466, 2017 03 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28352114
16.
Discovery of a Highly Selective STK16 Kinase Inhibitor.
ACS Chem Biol
; 11(6): 1537-43, 2016 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27082499
17.
High versus low vancomycin serum trough regimen for Gram-positive infections: a meta-analysis.
J Chemother
; 27(4): 213-20, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24641266
18.
Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by small-molecule inhibition of IGF1R.
Clin Cancer Res
; 20(21): 5483-95, 2014 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25186968
19.
Discovery of a potent, covalent BTK inhibitor for B-cell lymphoma.
ACS Chem Biol
; 9(5): 1086-91, 2014 May 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-24556163
20.
Aliskiren vs. other antihypertensive drugs in the treatment of hypertension: a meta-analysis.
Hypertens Res
; 36(3): 252-61, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23154589