Detalles de la búsqueda
1.
N-Terminomic Changes in Neurons During Excitotoxicity Reveal Proteolytic Events Associated With Synaptic Dysfunctions and Potential Targets for Neuroprotection.
Mol Cell Proteomics
; 22(5): 100543, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37030595
2.
Phosphomatics: interactive interrogation of substrate-kinase networks in global phosphoproteomics datasets.
Bioinformatics
; 37(11): 1635-1636, 2021 07 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33119075
3.
The structure of the extracellular domains of human interleukin 11α receptor reveals mechanisms of cytokine engagement.
J Biol Chem
; 295(24): 8285-8301, 2020 06 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32332100
4.
The Roc-COR tandem domain of leucine-rich repeat kinase 2 forms dimers and exhibits conventional Ras-like GTPase properties.
J Neurochem
; 147(3): 409-428, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30091236
5.
Csk-homologous kinase (Chk) is an efficient inhibitor of Src-family kinases but a poor catalyst of phosphorylation of their C-terminal regulatory tyrosine.
Cell Commun Signal
; 15(1): 29, 2017 08 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28784162
6.
Activation of Src family tyrosine kinases by ferric ions.
Biochim Biophys Acta
; 1844(3): 487-96, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24334106
7.
The C-terminal tail inhibitory phosphorylation sites of PTEN regulate its intrinsic catalytic activity and the kinetics of its binding to phosphatidylinositol-4,5-bisphosphate.
Arch Biochem Biophys
; 587: 48-60, 2015 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26471078
8.
Prediction of the repeat domain structures and impact of parkinsonism-associated variations on structure and function of all functional domains of leucine-rich repeat kinase 2 (LRRK2).
Hum Mutat
; 35(4): 395-412, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24470158
9.
Global analysis of human nonreceptor tyrosine kinase specificity using high-density peptide microarrays.
J Proteome Res
; 13(10): 4339-46, 2014 Oct 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-25164267
10.
A truncated fragment of Src protein kinase generated by calpain-mediated cleavage is a mediator of neuronal death in excitotoxicity.
J Biol Chem
; 288(14): 9696-9709, 2013 Apr 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23400779
11.
The GHB analogue HOCPCA improves deficits in cognition and sensorimotor function after MCAO via CaMKIIα.
J Cereb Blood Flow Metab
; 43(8): 1419-1434, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37026450
12.
Analysis of the regulatory and catalytic domains of PTEN-induced kinase-1 (PINK1).
Hum Mutat
; 33(10): 1408-22, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22644621
13.
Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations.
Biochem Soc Trans
; 40(5): 1086-9, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22988870
14.
Aberrant regulation and function of Src family tyrosine kinases: their potential contributions to glutamate-induced neurotoxicity.
Clin Exp Pharmacol Physiol
; 39(8): 684-91, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-21973029
15.
Characterization of a novel JNK (c-Jun N-terminal kinase) inhibitory peptide.
Biochem J
; 434(3): 399-413, 2011 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21162712
16.
Defining the substrate specificity determinants recognized by the active site of C-terminal Src kinase-homologous kinase (CHK) and identification of ß-synuclein as a potential CHK physiological substrate.
Biochemistry
; 50(31): 6667-77, 2011 Aug 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-21699177
17.
Unique biochemical properties of the protein tyrosine phosphatase activity of PTEN-demonstration of different active site structural requirements for phosphopeptide and phospholipid phosphatase activities of PTEN.
Biochim Biophys Acta
; 1804(9): 1785-95, 2010 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-20685300
18.
A facile, click chemistry-based approach to assembling fluorescent chemosensors for protein tyrosine kinases.
Bioorg Med Chem Lett
; 21(1): 329-31, 2011 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21111620
19.
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation.
Oncogene
; 40(17): 3015-3029, 2021 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-33767439
20.
Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases.
Growth Factors
; 28(5): 329-50, 2010 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-20476842