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Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
Bioorg Chem
; 102: 104003, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32771768
2.
Phytogenic Polyphenols as Glycogen Phosphorylase Inhibitors: The Potential of Triterpenes and Flavonoids for Glycaemic Control in Type 2 Diabetes.
Curr Med Chem
; 24(4): 384-403, 2017.
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en Inglés
| MEDLINE | ID: mdl-27855623
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