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1.
Time-varying brentuximab vedotin pharmacokinetics and weight-based dosing in paediatric patients despite lower exposure in those aged 2 to <6 and 6-11 years.
Br J Clin Pharmacol
; 2024 Jun 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-38866401
2.
Population pharmacokinetic modelling of tremelimumab in patients with advanced solid tumours and the impact of disease status on time-varying clearance.
Br J Clin Pharmacol
; 89(5): 1601-1616, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36454221
3.
Phase II randomised trial of type I interferon inhibitor anifrolumab in patients with active lupus nephritis.
Ann Rheum Dis
; 81(4): 496-506, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35144924
4.
Relationship of anifrolumab pharmacokinetics with efficacy and safety in patients with systemic lupus erythematosus.
Rheumatology (Oxford)
; 61(5): 1900-1910, 2022 05 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34528084
5.
Exposure-response analysis for selection of optimal dosage regimen of anifrolumab in patients with systemic lupus erythematosus.
Rheumatology (Oxford)
; 60(12): 5854-5862, 2021 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33629110
6.
Population pharmacokinetics, efficacy, and safety of moxetumomab pasudotox in patients with relapsed or refractory hairy cell leukaemia.
Br J Clin Pharmacol
; 86(7): 1367-1376, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32077130
7.
Two schedules of etirinotecan pegol (NKTR-102) in patients with previously treated metastatic breast cancer: a randomised phase 2 study.
Lancet Oncol
; 14(12): 1216-25, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-24095299
8.
Exposure-Response and Subgroup Analyses to Support Body Weight-Based Dosing of Brentuximab Vedotin in Children and Young Adults with Newly Diagnosed High-Risk Classical Hodgkin Lymphoma.
Clin Cancer Res
; 2024 May 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38810021
9.
Safety, Tolerability, and Pharmacokinetics of Benralizumab: A Phase 1, Randomized, Single-Blind Study of Healthy Chinese Participants.
Drug Des Devel Ther
; 17: 209-218, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36726737
10.
Nonlinear Population Pharmacokinetics of Anifrolumab in Healthy Volunteers and Patients With Systemic Lupus Erythematosus.
J Clin Pharmacol
; 62(9): 1106-1120, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35383948
11.
Relationship Between Anifrolumab Pharmacokinetics, Pharmacodynamics, and Efficacy in Patients With Moderate to Severe Systemic Lupus Erythematosus.
J Clin Pharmacol
; 62(9): 1094-1105, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35352835
12.
Pharmacokinetics, pharmacodynamics, and safety of subcutaneous anifrolumab in patients with systemic lupus erythematosus, active skin disease, and high type I interferon gene signature: a multicentre, randomised, double-blind, placebo-controlled, phase 2 study.
Lancet Rheumatol
; 3(2): e101-e110, 2021 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38279367
13.
A therapeutic drug monitoring algorithm for refining the imatinib trough level obtained at different sampling times.
Ther Drug Monit
; 31(5): 579-84, 2009 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-19730279
14.
Population Pharmacokinetic Modeling of Benralizumab in Adult and Adolescent Patients with Asthma.
Clin Pharmacokinet
; 58(7): 943-958, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30854591
15.
Relationship Between Benralizumab Exposure and Efficacy for Patients With Severe Eosinophilic Asthma.
Clin Pharmacol Ther
; 106(2): 383-390, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30661249
16.
Integrated population pharmacokinetics of etirinotecan pegol and its four metabolites in cancer patients with solid tumors.
Cancer Chemother Pharmacol
; 81(5): 897-909, 2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29564497
17.
Simulation-based parameter estimation for complex models: a breast cancer natural history modelling illustration.
Stat Methods Med Res
; 13(6): 507-24, 2004 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-15587436
18.
The effect of age, race, tumor size, tumor grade, and disease stage on invasive ductal breast cancer survival in the U.S. SEER database.
Breast Cancer Res Treat
; 89(1): 47-54, 2005 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-15666196
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