Detalles de la búsqueda
1.
Comparative Evaluation of Particle Size Reduction, Salt Formation, and Amorphous Formulation on the Biopharmaceutical Performance of a Weak Base Drug Candidate.
Mol Pharm
; 20(11): 5888-5900, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37792707
2.
Improving puncture accuracy in percutaneous CT-guided needle insertion with wireless inertial measurement unit: a phantom study.
Eur Radiol
; 33(5): 3156-3164, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-36826496
3.
Filling a nick in NIK: Extending the half-life of a NIK inhibitor through structure-based drug design.
Bioorg Med Chem Lett
; 89: 129277, 2023 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37105490
4.
Modeling Drug Dissolution in 3-Dimensional Space.
Pharm Res
; 39(5): 907-917, 2022 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-35474157
5.
Evaluating Utilization of Tiny-TIM to Assess the Effect of Food on the Absorptions of Oral Drugs and Its Application on Biopharmaceutical Modeling.
J Pharm Sci
; 113(6): 1586-1596, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38266915
6.
Development of an extemporaneous preparation formulation using a simple and non-solubilizing matrix for first in human clinical study.
Int J Pharm
; 653: 123868, 2024 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38309485
7.
Systemic concentrations can limit the oral absorption of poorly soluble drugs: an investigation of non-sink permeation using physiologically based pharmacokinetic modeling.
Mol Pharm
; 10(11): 3980-8, 2013 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-23611122
8.
Exploring the Use of a Kinetic pH Calculation to Correct the ACAT Model with a Single Stomach Compartment Setting: Impact of Stomach Setting on Food Effect Prediction for Basic Compounds.
J Pharm Sci
; 112(7): 1888-1896, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-36796637
9.
Early drainage reduces the length of hospital stay in patients with lung abscess.
Front Med (Lausanne)
; 10: 1206419, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37731714
10.
Novel nanoparticles formulation for cassette dosing via intravenous injection in rats for high throughput pharmacokinetic screening and potential applications.
J Nanosci Nanotechnol
; 12(10): 7993-8000, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23421169
11.
Evaluation of drug load and polymer by using a 96-well plate vacuum dry system for amorphous solid dispersion drug delivery.
AAPS PharmSciTech
; 13(2): 713-22, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22562615
12.
Evaluating the IVIVC by Combining Tiny-tim Outputs and Compartmental PK Model to Predict Oral Exposure for Different Formulations of Ibuprofen.
J Pharm Sci
; 111(7): 2018-2029, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35120962
13.
Elucidating a Potential Mechanism of Permeability Enhancer Sodium N-[8-(2-hydroxybenzoyl) amino] Caprylate in Rats: Evidence of Lymphatic Absorption of Cyanocobalamin using the Mesenteric Lymph Duct Cannulated Rat.
J Pharm Sci
; 111(12): 3417-3423, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36228756
14.
Mechanistic Oral Absorption Modeling of Halofantrine: Exploring the Role of Intestinal Lymphatic Transport.
J Pharm Sci
; 110(3): 1427-1430, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-33359312
15.
Utilizing Tiny-TIM to Assess the Effect of Acid-Reducing Agents on the Absorption of Orally Administered Drugs.
J Pharm Sci
; 110(8): 3020-3026, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33940027
16.
Impact of surfactant selection and incorporation on in situ nanoparticle formation from amorphous solid dispersions.
Int J Pharm
; 607: 120980, 2021 Sep 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34371147
17.
Automated Radiology Alert System for Pneumothorax Detection on Chest Radiographs Improves Efficiency and Diagnostic Performance.
Diagnostics (Basel)
; 11(7)2021 Jun 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-34209844
18.
Exploring Multicompartment Plug Flow-Based Model Approach in Biopharmaceutics: Impact of Stomach Setting and the Estimation of the Fraction Absorbed of Orally Administered Basic Drugs.
J Pharm Sci
; 109(3): 1261-1269, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31836377
19.
A Physiologically Based Pharmacokinetic Model of Vismodegib: Deconvoluting the Impact of Saturable Plasma Protein Binding, pH-Dependent Solubility and Nonsink Permeation.
AAPS J
; 22(5): 117, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32875428
20.
Understanding the Effect of Hydroxypropyl-ß-Cyclodextrin on Fenebrutinib Absorption in an Itraconazole-Fenebrutinib Drug-Drug Interaction Study.
Clin Pharmacol Ther
; 108(6): 1224-1232, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32535897