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1.
Quantitative Model Analysis and Simulation of Pharmacokinetics and Metastasis-Associated Lung Adenocarcinoma 1 RNA Knockdown Effect After Systemic Administration of Cholesterol-Conjugated DNA/RNA Heteroduplex Oligonucleotide Crossing Blood-Brain Barrier of Mice.
J Pharmacol Exp Ther
; 384(1): 197-204, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36273821
2.
Characterization of plasma protein binding in two mouse models of humanized liver, PXB mouse and humanized TK-NOG mouse.
Xenobiotica
; 51(1): 51-60, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-32779988
3.
Prediction of human pharmacokinetics of long half-life compounds using chimeric mice with humanised liver.
Xenobiotica
; 49(12): 1379-1387, 2019 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30744481
4.
Identification of a novel series of potent and selective CCR6 inhibitors as biological probes.
Bioorg Med Chem Lett
; 28(18): 3067-3072, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30098865
5.
Fluid shear stress stimulates MATE2-K expression via Nrf2 pathway activation.
Biochem Biophys Res Commun
; 484(2): 358-364, 2017 03 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28131833
6.
Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling of the Glucagon-Like Peptide-1 Receptor Agonist Exenatide to Characterize Its Antiobesity Effects in Diet-Induced Obese Mice.
J Pharmacol Exp Ther
; 362(3): 441-449, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28698254
7.
Comparison of predictability for human pharmacokinetics parameters among monkeys, rats, and chimeric mice with humanised liver.
Xenobiotica
; 47(12): 1052-1063, 2017 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-27892765
8.
Utility of Göttingen minipigs for the prediction of human pharmacokinetic profiles after intravenous drug administration.
Drug Metab Pharmacokinet
; 41: 100408, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34710650
9.
Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.
Biochim Biophys Acta
; 1788(11): 2396-403, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19728987
10.
Relationship of MATE1 Inhibition and Cytotoxicity in Nephrotoxicity: Application for Safety Evaluation in Early Drug Discovery.
Toxicol Sci
; 170(1): 223-233, 2019 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31020312
11.
Association between risk of myopathy and cholesterol-lowering effect: a comparison of all statins.
Life Sci
; 82(17-18): 969-75, 2008 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-18402982
12.
Corrigendum to "Utility of Göttingen minipigs for the prediction of human pharmacokinetic profiles after intravenous drug administration" [Drug Metabol Pharmacokinet 41 (2021) 100408].
Drug Metab Pharmacokinet
; 57: 100508, 2023 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38851060
13.
Identification and Characterization of a New Series of Ghrelin O-Acyl Transferase Inhibitors.
SLAS Discov
; 23(2): 154-163, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-28846466
14.
Regulation of multidrug resistance protein 2 (MRP2, ABCC2) expression by statins: involvement of SREBP-mediated gene regulation.
Int J Pharm
; 452(1-2): 36-41, 2013 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23612356
15.
[Effects of acidification and alkalinization agents on statins-induced muscle toxicity].
Yakugaku Zasshi
; 132(5): 609-15, 2012.
Artículo
en Japonés
| MEDLINE | ID: mdl-22687697
16.
Regulation mechanism of ABCA1 expression by statins in hepatocytes.
Eur J Pharmacol
; 662(1-3): 9-14, 2011 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21554872
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