Detalles de la búsqueda
1.
USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity.
Mol Med
; 28(1): 164, 2022 12 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36585612
2.
Pharmacokinetic modeling analysis of cilostazol and its active metabolites (OPC-13015 and OPC-13213) after multiple oral doses of cilostazol in healthy Korean volunteers.
Xenobiotica
; 50(3): 288-296, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-31181990
3.
Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of CTB-001, a Recently Developed Generic of Bivalirudin.
Pharm Res
; 36(10): 146, 2019 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31396727
4.
Impact of CYP2D6, CYP3A5, CYP2C19, CYP2A6, SLCO1B1, ABCB1, and ABCG2 gene polymorphisms on the pharmacokinetics of simvastatin and simvastatin acid.
Pharmacogenet Genomics
; 25(12): 595-608, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26367500
5.
Therapeutic dosage assessment based on population pharmacokinetics of a novel single-dose transdermal donepezil patch in healthy volunteers.
Eur J Clin Pharmacol
; 71(8): 967-77, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26014587
6.
Effects of food on the pharmacokinetics of gemigliptin/metformin sustained-release 50/1,000 mg (25/500 mg x 2 tablets) fixeddose combination tablet in healthy male volunteers.
Int J Clin Pharmacol Ther
; 52(5): 381-91, 2014 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-24495314
7.
Comparison of Pharmacodynamics between Tegoprazan and Dexlansoprazole Regarding Nocturnal Acid Breakthrough: A Randomized Crossover Study.
Gut Liver
; 17(1): 92-99, 2023 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36317518
8.
Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of Prasugrel in Healthy Male Volunteers.
Clin Pharmacol Drug Dev
; 12(1): 21-29, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36251178
9.
USP13 deubiquitinates p62/SQSTM1 to induce autophagy and Nrf2 release for activating antioxidant response genes.
Free Radic Biol Med
; 208: 820-832, 2023 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37776917
10.
Effect of Food on the Pharmacokinetics and Pharmacodynamics of a Single Oral Dose of Tegoprazan.
Clin Ther
; 43(8): 1371-1380, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34246485
11.
First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of a Neuroprotective Poly (ADP-ribose) Polymerase-1 Inhibitor, JPI-289, in Healthy Volunteers.
Drug Des Devel Ther
; 14: 3189-3199, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32801651
12.
The risk of stroke/systemic embolism and major bleeding in Asian patients with non-valvular atrial fibrillation treated with non-vitamin K oral anticoagulants compared to warfarin: Results from a real-world data analysis.
PLoS One
; 15(11): e0242922, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33253294
13.
Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ-12420), a novel potassium-competitive acid blocker, in healthy male subjects.
Aliment Pharmacol Ther
; 50(7): 751-759, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31437865
14.
Quantitative Modeling Analysis Demonstrates the Impact of CYP2C19 and CYP2D6 Genetic Polymorphisms on the Pharmacokinetics of Amitriptyline and Its Metabolite, Nortriptyline.
J Clin Pharmacol
; 59(4): 532-540, 2019 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-30452773
15.
A randomized study of the efficacy and safety of parecoxib for the treatment of pain following total knee arthroplasty in Korean patients.
J Pain Res
; 11: 427-433, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29503579
16.
Pharmacokinetic interactions and tolerability of rosuvastatin and ezetimibe: an open-label, randomized, multiple-dose, crossover study in healthy male volunteers.
Drug Des Devel Ther
; 12: 815-821, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29692602
17.
Population plasma and urine pharmacokinetics of ivabradine and its active metabolite S18982 in healthy Korean volunteers.
J Clin Pharmacol
; 56(4): 439-49, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26265098
18.
Pharmacokinetic comparison of sustained- and immediate-release formulations of cilostazol after multiple oral doses in fed healthy male Korean volunteers.
Drug Des Devel Ther
; 9: 3571-7, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26185423
19.
Single and multiple dose pharmacokinetics and tolerability of HX-1171, a novel antioxidant, in healthy volunteers.
Drug Des Devel Ther
; 9: 1735-42, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25848210
20.
Dose proportionality and pharmacokinetics of carvedilol sustained-release formulation: a single dose-ascending 10-sequence incomplete block study.
Drug Des Devel Ther
; 9: 2911-8, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26089641