Detalles de la búsqueda
1.
(R)-2-Phenylpyrrolidine Substituted Imidazopyridazines: A New Class of Potent and Selective Pan-TRK Inhibitors.
ACS Med Chem Lett
; 6(5): 562-7, 2015 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-26005534
2.
Synthesis, structure-activity relationships, and in vivo efficacy of the novel potent and selective anaplastic lymphoma kinase (ALK) inhibitor 5-chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) currently in phase 1 and phase 2 clinical trials.
J Med Chem
; 56(14): 5675-90, 2013 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-23742252
3.
Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.
Proc Natl Acad Sci U S A
; 104(1): 270-5, 2007 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-17185414
Resultados
1 -
3
de 3
1
Próxima >
>>