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1.
Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension.
J Pharmacol Exp Ther
; 383(1): 103-116, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36507843
2.
Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections.
Antimicrob Agents Chemother
; 65(7): e0031621, 2021 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33941518
3.
Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats.
Pulm Pharmacol Ther
; 66: 101983, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33346142
4.
Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension.
Int J Mol Sci
; 22(2)2021 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33430435
5.
Correction for Plaunt et al., "Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections".
Antimicrob Agents Chemother
; 66(11): e0125622, 2022 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36222535
6.
Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice.
Front Immunol
; 14: 1185727, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37441081
7.
The pharmacokinetic profile of brensocatib and its effect on pharmacodynamic biomarkers including NE, PR3, and CatG in various rodent species.
Front Pharmacol
; 14: 1208780, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37538173
8.
Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection.
Pharmaceutics
; 15(9)2023 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37765219
9.
Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension.
Eur J Pharmacol
; 916: 174484, 2022 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34508752
10.
A cell-based assay for screening the uridine 5(')-diphosphate-glucuronosyltransferase 1A inhibitory potential of new chemical entities.
Anal Biochem
; 320(2): 310-2, 2003 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-12927840
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