Detalles de la búsqueda
1.
Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist.
N Engl J Med
; 377(1): 28-40, 2017 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28525302
2.
Uterine NK cells regulate endometrial bleeding in women and are suppressed by the progesterone receptor modulator asoprisnil.
J Immunol
; 191(5): 2226-35, 2013 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23913972
3.
Clinical development of the GnRH agonist leuprolide acetate depot.
F S Rep
; 4(2 Suppl): 33-39, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37223757
4.
Clinical development of the oral gonadotropin-releasing hormone antagonist elagolix.
F S Rep
; 4(2 Suppl): 65-72, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37223767
5.
Endometriosis-Related Pain Reduction During Bleeding and Nonbleeding Days in Women Treated with Elagolix.
J Pain Res
; 14: 263-271, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33564263
6.
Elagolix Suppresses Ovulation in a Dose-Dependent Manner: Results From a 3-Month, Randomized Study in Ovulatory Women.
J Clin Endocrinol Metab
; 105(3)2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31650182
7.
Selective progesterone receptor modulator development and use in the treatment of leiomyomata and endometriosis.
Endocr Rev
; 26(3): 423-38, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15857972
8.
Clinical evaluation of the oral gonadotropin-releasing hormone-antagonist elagolix for the management of endometriosis-associated pain.
Pain Manag
; 9(5): 497-515, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31434540
9.
Effects of the selective progesterone receptor modulator asoprisnil on uterine artery blood flow, ovarian activity, and clinical symptoms in patients with uterine leiomyomata scheduled for hysterectomy.
J Clin Endocrinol Metab
; 93(12): 4664-71, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-18765509
10.
Selective progesterone receptor modulator asoprisnil down-regulates collagen synthesis in cultured human uterine leiomyoma cells through up-regulating extracellular matrix metalloproteinase inducer.
Hum Reprod
; 23(4): 944-51, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18281245
11.
Development and Validation of the Endometriosis Daily Pain Impact Diary Items to Assess Dysmenorrhea and Nonmenstrual Pelvic Pain.
Reprod Sci
; 25(11): 1567-1576, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30033855
12.
Elagolix Alone or With Add-Back Therapy in Women With Heavy Menstrual Bleeding and Uterine Leiomyomas: A Randomized Controlled Trial.
Obstet Gynecol
; 132(5): 1252-1264, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30303923
13.
Long-Term Outcomes of Elagolix in Women With Endometriosis: Results From Two Extension Studies.
Obstet Gynecol
; 132(1): 147-160, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29889764
14.
A novel selective progesterone receptor modulator asoprisnil activates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated signaling pathway in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.
J Clin Endocrinol Metab
; 92(2): 616-23, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17105846
15.
Antiprogestin-releasing intrauterine devices: a novel approach to endometrial contraception.
Contraception
; 75(6 Suppl): S104-11, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17531599
16.
Dose-Dependent Suppression of Gonadotropins and Ovarian Hormones by Elagolix in Healthy Premenopausal Women.
J Clin Endocrinol Metab
; 102(5): 1683-1691, 2017 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28323948
17.
Validation of the 4 week recall version of the Uterine Fibroid Symptom and Health-related Quality of Life (UFS-QOL) Questionnaire.
Curr Med Res Opin
; 33(2): 193-200, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27733082
18.
Elagolix for the management of heavy menstrual bleeding associated with uterine fibroids: results from a phase 2a proof-of-concept study.
Fertil Steril
; 108(1): 152-160.e4, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28579415
19.
A novel selective progesterone receptor modulator asoprisnil (J867) inhibits proliferation and induces apoptosis in cultured human uterine leiomyoma cells in the absence of comparable effects on myometrial cells.
J Clin Endocrinol Metab
; 91(4): 1296-304, 2006 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-16464945
20.
Role of nonhuman primate models in the discovery and clinical development of selective progesterone receptor modulators (SPRMs).
Reprod Biol Endocrinol
; 4 Suppl 1: S8, 2006.
Artículo
en Inglés
| MEDLINE | ID: mdl-17118172