Detalles de la búsqueda
1.
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.
Pharmacol Rev
; 73(1): 310-520, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33370241
2.
Development of Pleiotropic TrkB and 5-HT4 Receptor Ligands as Neuroprotective Agents.
Molecules
; 29(2)2024 Jan 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38276593
3.
Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease.
Molecules
; 24(15)2019 Jul 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31370232
4.
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment.
Proc Natl Acad Sci U S A
; 111(36): E3825-30, 2014 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-25157130
5.
Cerebrovascular pathology during the progression of experimental Alzheimer's disease.
Neurobiol Dis
; 88: 107-17, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26774030
6.
Beta-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling.
EMBO J
; 28(18): 2706-18, 2009 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19661922
7.
G protein activation by serotonin type 4 receptor dimers: evidence that turning on two protomers is more efficient.
J Biol Chem
; 286(12): 9985-97, 2011 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-21247891
8.
Engineering GPCR signaling pathways with RASSLs.
Nat Methods
; 5(8): 673-8, 2008 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-18668035
9.
Novel and atypical pathways for serotonin signaling.
Fac Rev
; 10: 52, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34195691
10.
Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease.
Eur J Med Chem
; 210: 113059, 2021 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33310288
11.
5-hydroxytryptamine 4 receptor activation of the extracellular signal-regulated kinase pathway depends on Src activation but not on G protein or beta-arrestin signaling.
Mol Biol Cell
; 18(6): 1979-91, 2007 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-17377064
12.
Peripheral Routes to Neurodegeneration: Passing Through the Blood-Brain Barrier.
Front Aging Neurosci
; 12: 3, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32116645
13.
Therapeutic modulators of the serotonin 5-HT4 receptor: a patent review (2014-present).
Expert Opin Ther Pat
; 30(7): 495-508, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32400221
14.
Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease.
Sci Rep
; 10(1): 3014, 2020 02 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32080261
15.
Donecopride, a Swiss army knife with potential against Alzheimer's disease.
Br J Pharmacol
; 177(9): 1988-2005, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31881553
16.
Conformational toggle switches implicated in basal constitutive and agonist-induced activated states of 5-hydroxytryptamine-4 receptors.
Mol Pharmacol
; 75(4): 982-90, 2009 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-19168624
17.
A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer's Disease.
Front Aging Neurosci
; 11: 148, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31316368
18.
Novel multi target-directed ligands targeting 5-HT4 receptors with in cellulo antioxidant properties as promising leads in Alzheimer's disease.
Eur J Med Chem
; 182: 111596, 2019 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31419776
19.
5-HT(4) receptors: history, molecular pharmacology and brain functions.
Neuropharmacology
; 55(6): 922-31, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18603269
20.
Phosphorylation of ß-arrestin2 at Thr383 by MEK underlies ß-arrestin-dependent activation of Erk1/2 by GPCRs.
Elife
; 62017 02 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28169830