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1.
Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia.
Antimicrob Agents Chemother
; 57(6): 2526-34, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23507282
2.
Population pharmacokinetics of fusidic acid: rationale for front-loaded dosing regimens due to autoinhibition of clearance.
Antimicrob Agents Chemother
; 57(1): 498-507, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23147726
3.
Comparison of plasma, epithelial lining fluid, and alveolar macrophage concentrations of solithromycin (CEM-101) in healthy adult subjects.
Antimicrob Agents Chemother
; 56(10): 5076-81, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22802254
4.
Pharmacokinetics and safety of single, multiple, and loading doses of fusidic acid in healthy subjects.
Clin Infect Dis
; 52 Suppl 7: S504-12, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21546627
5.
A randomized, double-blind phase 2 study comparing the efficacy and safety of an oral fusidic acid loading-dose regimen to oral linezolid for the treatment of acute bacterial skin and skin structure infections.
Clin Infect Dis
; 52 Suppl 7: S520-6, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21546629
6.
Pharmacokinetics of solithromycin (CEM-101) after single or multiple oral doses and effects of food on single-dose bioavailability in healthy adult subjects.
Antimicrob Agents Chemother
; 55(5): 1997-2003, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21282444
7.
Efficacy and safety of oral solithromycin versus oral moxifloxacin for treatment of community-acquired bacterial pneumonia: a global, double-blind, multicentre, randomised, active-controlled, non-inferiority trial (SOLITAIRE-ORAL).
Lancet Infect Dis
; 16(4): 421-30, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26852726
8.
A phase 2, open-label study of the safety and efficacy of intravenous anidulafungin as a treatment for azole-refractory mucosal candidiasis.
J Acquir Immune Defic Syndr
; 48(3): 304-9, 2008 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18545153
9.
Safety and pharmacokinetics of intravenous anidulafungin in children with neutropenia at high risk for invasive fungal infections.
Antimicrob Agents Chemother
; 50(2): 632-8, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16436720
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