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1.
Quantitative NMR analysis of the mechanism and kinetics of chaperone Hsp104 action on amyloid-ß42 aggregation and fibril formation.
Proc Natl Acad Sci U S A
; 120(21): e2305823120, 2023 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-37186848
2.
Quantitative analysis of sterol-modulated monomer-dimer equilibrium of the ß1-adrenergic receptor by DEER spectroscopy.
Proc Natl Acad Sci U S A
; 120(7): e2221036120, 2023 02 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36745787
3.
Quantitative NMR analysis of the kinetics of prenucleation oligomerization and aggregation of pathogenic huntingtin exon-1 protein.
Proc Natl Acad Sci U S A
; 119(29): e2207690119, 2022 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35858329
4.
Time-resolved DEER EPR and solid-state NMR afford kinetic and structural elucidation of substrate binding to Ca2+-ligated calmodulin.
Proc Natl Acad Sci U S A
; 119(6)2022 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35105816
5.
Interaction of the bacterial division regulator MinE with lipid bicelles studied by NMR spectroscopy.
J Biol Chem
; 299(4): 103037, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36806683
6.
NMR spectroscopy, excited states and relevance to problems in cell biology - transient pre-nucleation tetramerization of huntingtin and insights into Huntington's disease.
J Cell Sci
; 135(12)2022 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35703323
7.
Atomic view of cosolute-induced protein denaturation probed by NMR solvent paramagnetic relaxation enhancement.
Proc Natl Acad Sci U S A
; 118(34)2021 08 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34404723
8.
A methyl-TROSY based 13C relaxation dispersion NMR experiment for studies of chemical exchange in proteins.
J Biomol NMR
; 77(3): 83-91, 2023 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-37095392
9.
An S/T motif controls reversible oligomerization of the Hsp40 chaperone DNAJB6b through subtle reorganization of a ß sheet backbone.
Proc Natl Acad Sci U S A
; 117(48): 30441-30450, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33199640
10.
Abrogation of prenucleation, transient oligomerization of the Huntingtin exon 1 protein by human profilin I.
Proc Natl Acad Sci U S A
; 117(11): 5844-5852, 2020 03 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32127471
11.
Quantitative Agreement between Conformational Substates of Holo Calcium-Loaded Calmodulin Detected by Double Electron-Electron Resonance EPR and Predicted by Molecular Dynamics Simulations.
J Am Chem Soc
; 144(27): 12043-12051, 2022 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35759799
12.
Theory and Applications of Nitroxide-based Paramagnetic Cosolutes for Probing Intermolecular and Electrostatic Interactions on Protein Surfaces.
J Am Chem Soc
; 144(46): 21371-21388, 2022 11 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-36346613
13.
Unraveling the structure and dynamics of the human DNAJB6b chaperone by NMR reveals insights into Hsp40-mediated proteostasis.
Proc Natl Acad Sci U S A
; 116(43): 21529-21538, 2019 10 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-31591220
14.
Spatial domain organization in the HIV-1 reverse transcriptase p66 homodimer precursor probed by double electron-electron resonance EPR.
Proc Natl Acad Sci U S A
; 116(36): 17809-17816, 2019 09 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31383767
15.
Probing transient excited states of the bacterial cell division regulator MinE by relaxation dispersion NMR spectroscopy.
Proc Natl Acad Sci U S A
; 116(51): 25446-25455, 2019 12 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31772021
16.
Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR.
Proc Natl Acad Sci U S A
; 116(9): 3562-3571, 2019 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30808748
17.
Microsecond Backbone Motions Modulate the Oligomerization of the DNAJB6 Chaperone.
Angew Chem Int Ed Engl
; 61(20): e202116403, 2022 05 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35247211
18.
Quantitative Exchange NMR-Based Analysis of Huntingtin-SH3 Interactions Suggests an Allosteric Mechanism of Inhibition of Huntingtin Aggregation.
J Am Chem Soc
; 143(25): 9672-9681, 2021 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-34137596
19.
A simple and cost-effective protocol for high-yield expression of deuterated and selectively isoleucine/leucine/valine methyl protonated proteins in Escherichia coli grown in shaker flasks.
J Biomol NMR
; 75(2-3): 83-87, 2021 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-33538948
20.
Probing the Interaction of Huntingtin Exon-1 Polypeptides with the Chaperonin Nanomachine GroEL.
Chembiochem
; 22(11): 1985-1991, 2021 06 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33644966