Detalles de la búsqueda
1.
Poly(N-vinylpyrrolidone) Antimalaria Conjugates of Membrane-Disruptive Peptides.
Biomacromolecules
; 21(12): 5053-5066, 2020 12 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33156615
2.
Artemisone and Artemiside Are Potent Panreactive Antimalarial Agents That Also Synergize Redox Imbalance in Plasmodium falciparum Transmissible Gametocyte Stages.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29866868
3.
Synthesis, antimalarial activities and cytotoxicities of amino-artemisinin-1,2-disubstituted ferrocene hybrids.
Bioorg Med Chem Lett
; 28(19): 3161-3163, 2018 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30174153
4.
Synthesis, in vitro antimalarial activities and cytotoxicities of amino-artemisinin-ferrocene derivatives.
Bioorg Med Chem Lett
; 28(3): 289-292, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29317166
5.
Straightforward conversion of decoquinate into inexpensive tractable new derivatives with significant antimalarial activities.
Bioorg Med Chem Lett
; 26(13): 3006-3009, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27210430
6.
hERG, Plasmodium Life Cycle, and Cross Resistance Profiling of New Azabenzimidazole Analogues of Astemizole.
ACS Med Chem Lett
; 15(4): 463-469, 2024 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-38628794
7.
Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.
ACS Infect Dis
; 9(2): 342-364, 2023 02 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36706233
8.
Antimalarial and antitumour activities of the steroidal quinone-methide celastrol and its combinations with artemiside, artemisone and methylene blue.
Front Pharmacol
; 13: 988748, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36120293
9.
Novel 3-Trifluoromethyl-1,2,4-oxadiazole Analogues of Astemizole with Multi-stage Antiplasmodium Activity and In Vivo Efficacy in a Plasmodium berghei Mouse Malaria Infection Model.
J Med Chem
; 65(24): 16695-16715, 2022 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36507890
10.
The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages.
Sci Transl Med
; 14(667): eabo7219, 2022 10 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-36260689
11.
Antimalarial Benzimidazole Derivatives Incorporating Phenolic Mannich Base Side Chains Inhibit Microtubule and Hemozoin Formation: Structure-Activity Relationship and In Vivo Oral Efficacy Studies.
J Med Chem
; 64(8): 5198-5215, 2021 04 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-33844521
12.
The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage P. falciparum Parasites, DMPK Properties, and the Case for Artemiside.
Pharmaceutics
; 13(12)2021 Dec 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34959347
13.
Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against Plasmodium falciparum In Vitro.
ACS Med Chem Lett
; 12(8): 1333-1341, 2021 Aug 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34413963
14.
Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of Plasmodium falciparum Malaria Parasites.
ACS Infect Dis
; 7(7): 1945-1955, 2021 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33673735
15.
New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of Plasmodium Phosphatidylinositol-4-kinase and cGMP-Dependent Protein Kinase.
ACS Infect Dis
; 7(1): 34-46, 2021 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33319990
16.
Facile Route to Targeted, Biodegradable Polymeric Prodrugs for the Delivery of Combination Therapy for Malaria.
ACS Biomater Sci Eng
; 6(11): 6217-6227, 2020 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33449652
17.
Antimalarial N 1,N 3-Dialkyldioxonaphthoimidazoliums: Synthesis, Biological Activity, and Structure-activity Relationships.
ACS Med Chem Lett
; 11(1): 49-55, 2020 Jan 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31938463
18.
Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies-Activities Against Blood Stage P. falciparum Including PfKI3 C580Y Mutants and Liver Stage P. berghei Parasites.
Front Chem
; 7: 901, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31998692
19.
Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.
ChemMedChem
; 13(1): 67-77, 2018 01 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29193799
20.
Activities of 11-Azaartemisinin and N-Sulfonyl Derivatives against Asexual and Transmissible Malaria Parasites.
ChemMedChem
; 12(24): 2086-2093, 2017 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29219249