Detalles de la búsqueda
1.
The First Cytoplasmic Loop in the Core Structure of the ABCC1 (Multidrug Resistance Protein 1; MRP1) Transporter Contains Multiple Amino Acids Essential for Its Expression.
Int J Mol Sci
; 22(18)2021 Sep 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34575890
2.
Mutagenic Analysis of the Putative ABCC6 Substrate-Binding Cavity Using a New Homology Model.
Int J Mol Sci
; 22(13)2021 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-34199119
3.
Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1).
FASEB J
; 33(10): 10692-10704, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31268744
4.
An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1).
Mol Pharmacol
; 94(3): 1069-1078, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29976562
5.
Targeting multidrug resistance protein 1 (MRP1, ABCC1): past, present, and future.
Annu Rev Pharmacol Toxicol
; 54: 95-117, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24050699
6.
Arsenic Triglutathione [As(GS)3] Transport by Multidrug Resistance Protein 1 (MRP1/ABCC1) Is Selectively Modified by Phosphorylation of Tyr920/Ser921 and Glycosylation of Asn19/Asn23.
Mol Pharmacol
; 90(2): 127-39, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27297967
7.
N-linked glycans do not affect plasma membrane localization of multidrug resistance protein 4 (MRP4) but selectively alter its prostaglandin E2 transport activity.
Biochem Biophys Res Commun
; 469(4): 954-9, 2016 Jan 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-26721430
8.
Cysteinyl Leukotriene Receptor 1/2 Antagonists Nonselectively Modulate Organic Anion Transport by Multidrug Resistance Proteins (MRP1-4).
Drug Metab Dispos
; 44(6): 857-66, 2016 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-27068271
9.
Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.
J Biol Chem
; 289(45): 30880-8, 2014 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25281745
10.
Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter.
Biochim Biophys Acta
; 1838(3): 756-65, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24231430
11.
Naâº/H⺠exchanger regulatory factor 3 is critical for multidrug resistance protein 4-mediated drug efflux in the kidney.
J Am Soc Nephrol
; 25(4): 726-36, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24436471
12.
Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1).
J Biol Chem
; 287(10): 7543-55, 2012 Mar 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-22232552
13.
Two polymorphic variants of ABCC1 selectively alter drug resistance and inhibitor sensitivity of the multidrug and organic anion transporter multidrug resistance protein 1.
Drug Metab Dispos
; 41(12): 2187-96, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24080162
14.
Chalcogenopyrylium dyes as differential modulators of organic anion transport by multidrug resistance protein 1 (MRP1), MRP2, and MRP4.
Drug Metab Dispos
; 41(6): 1231-9, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23530018
15.
Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.
Nat Commun
; 14(1): 6868, 2023 10 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37891162
16.
Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain-domain coupling.
bioRxiv
; 2023 Oct 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37905074
17.
Expression and function of human MRP1 (ABCC1) is dependent on amino acids in cytoplasmic loop 5 and its interface with nucleotide binding domain 2.
J Biol Chem
; 286(9): 7202-13, 2011 Mar 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-21177244
18.
GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators.
FEBS J
; 289(13): 3854-3875, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35080351
19.
ABCC1 G2012T single nucleotide polymorphism is associated with patient outcome in primary neuroblastoma and altered stability of the ABCC1 gene transcript.
Pharmacogenet Genomics
; 21(5): 270-9, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21317832
20.
Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter.
PLoS One
; 16(2): e0246727, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33571281