Detalles de la búsqueda
1.
Elucidating the Mechanism of Action of the Attributed Immunomodulatory Role of Eltrombopag in Primary Immune Thrombocytopenia: An In Silico Approach.
Int J Mol Sci
; 22(13)2021 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-34199099
2.
Low levels of copper disrupt brain amyloid-ß homeostasis by altering its production and clearance.
Proc Natl Acad Sci U S A
; 110(36): 14771-6, 2013 Sep 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-23959870
3.
Clearance of amyloid-beta by circulating lipoprotein receptors.
Nat Med
; 13(9): 1029-31, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17694066
4.
Artificial intelligence assessment of the potential of tocilizumab along with corticosteroids therapy for the management of COVID-19 evoked acute respiratory distress syndrome.
PLoS One
; 18(2): e0280677, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36791125
5.
In silico evaluation of the role of lisdexamfetamine on attention-deficit/hyperactivity disorder common psychiatric comorbidities: mechanistic insights on binge eating disorder and depression.
Front Neurosci
; 17: 1118253, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37457000
6.
In silico clinical trial evaluating lisdexamfetamine's and methylphenidate's mechanism of action computational models in an attention-deficit/hyperactivity disorder virtual patients' population.
Front Psychiatry
; 14: 939650, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37333910
7.
Application of systems biology to identify pharmacological mechanisms of thrombotic microangiopathy evoked by combined activated prothrombin complex concentrate and emicizumab.
Sci Rep
; 13(1): 10078, 2023 06 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37344529
8.
Female Sex, Age, and Unfavorable Response to Tumor Necrosis Factor Inhibitors in Patients With Axial Spondyloarthritis: Results of Statistical and Artificial Intelligence-Based Data Analyses of a National Multicenter Prospective Registry.
Arthritis Care Res (Hoboken)
; 75(1): 115-124, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36278846
9.
Identification of the Potential Molecular Mechanisms Linking RUNX1 Activity with Nonalcoholic Fatty Liver Disease, by Means of Systems Biology.
Biomedicines
; 10(6)2022 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35740337
10.
Application of systems biology-based in silico tools to optimize treatment strategy identification in Still's disease.
Arthritis Res Ther
; 23(1): 126, 2021 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33892792
11.
Head to head evaluation of second generation ALK inhibitors brigatinib and alectinib as first-line treatment for ALK+ NSCLC using an in silico systems biology-based approach.
Oncotarget
; 12(4): 316-332, 2021 Feb 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33659043
12.
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation.
Brain
; 132(Pt 5): 1335-45, 2009 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-19251756
13.
In-silico drug repurposing study predicts the combination of pirfenidone and melatonin as a promising candidate therapy to reduce SARS-CoV-2 infection progression and respiratory distress caused by cytokine storm.
PLoS One
; 15(10): e0240149, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33006999
14.
Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming.
Front Endocrinol (Lausanne)
; 11: 258, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32477262
15.
Mild cholesterol depletion reduces amyloid-beta production by impairing APP trafficking to the cell surface.
J Neurochem
; 110(1): 220-30, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19457132
16.
Neuroprotective Drug for Nerve Trauma Revealed Using Artificial Intelligence.
Sci Rep
; 8(1): 1879, 2018 01 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-29382857
17.
The protective role of vitamin E in vascular amyloid beta-mediated damage.
Subcell Biochem
; 38: 147-65, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15709477
18.
Novel Neuroprotective Multicomponent Therapy for Amyotrophic Lateral Sclerosis Designed by Networked Systems.
PLoS One
; 11(1): e0147626, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26807587
19.
Impaired voltage-gated K+ channel expression in brain during experimental cancer cachexia.
FEBS Lett
; 536(1-3): 45-50, 2003 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-12586336
20.
The systemic inflammatory response is involved in the regulation of K(+) channel expression in brain via TNF-alpha-dependent and -independent pathways.
FEBS Lett
; 572(1-3): 189-94, 2004 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-15304346