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1.

Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.

Smets, Ide; Fiddes, Barnaby; Garcia-Perez, Josselyn E; He, Di; Mallants, Klara; Liao, Wenjia; Dooley, James; Wang, George; Humblet-Baron, Stephanie; Dubois, Bénédicte; Compston, Alastair; Jones, Joanne; Coles, Alasdair; Liston, Adrian; Ban, Maria; Goris, An; Sawcer, Stephen.

Brain ; 141(3): 786-796, 2018 03 01.

Artículo en Inglés | MEDLINE | ID: mdl-29361022

2.

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability.

Hunt, Karen A; Mistry, Vanisha; Bockett, Nicholas A; Ahmad, Tariq; Ban, Maria; Barker, Jonathan N; Barrett, Jeffrey C; Blackburn, Hannah; Brand, Oliver; Burren, Oliver; Capon, Francesca; Compston, Alastair; Gough, Stephen C L; Jostins, Luke; Kong, Yong; Lee, James C; Lek, Monkol; MacArthur, Daniel G; Mansfield, John C; Mathew, Christopher G; Mein, Charles A; Mirza, Muddassar; Nutland, Sarah; Onengut-Gumuscu, Suna; Papouli, Efterpi; Parkes, Miles; Rich, Stephen S; Sawcer, Steven; Satsangi, Jack; Simmonds, Matthew J; Trembath, Richard C; Walker, Neil M; Wozniak, Eva; Todd, John A; Simpson, Michael A; Plagnol, Vincent; van Heel, David A.

Nature ; 498(7453): 232-5, 2013 Jun 13.

Artículo en Inglés | MEDLINE | ID: mdl-23698362

3.

Reply: The etymology of 'neurology', redux: early use of the term by Jean Riolan the Younger (1610).

Mehta, Arpan R; Mehta, Puja R; Anderson, Stephen P; MacKinnon, Barbara L H; Compston, Alastair.

Brain ; 144(4): e39, 2021 05 07.

Artículo en Inglés | MEDLINE | ID: mdl-33837768

4.

Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.

Ossola, Bernardino; Zhao, Chao; Compston, Alastair; Pluchino, Stefano; Franklin, Robin J M; Spillantini, Maria Grazia.

Glia ; 64(3): 457-71, 2016 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-26576485

5.

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

Goris, An; van Setten, Jessica; Diekstra, Frank; Ripke, Stephan; Patsopoulos, Nikolaos A; Sawcer, Stephen J; van Es, Michael; Andersen, Peter M; Melki, Judith; Meininger, Vincent; Hardiman, Orla; Landers, John E; Brown, Robert H; Shatunov, Aleksey; Leigh, Nigel; Al-Chalabi, Ammar; Shaw, Christopher E; Traynor, Bryan J; Chiò, Adriano; Restagno, Gabriella; Mora, Gabriele; Ophoff, Roel A; Oksenberg, Jorge R; Van Damme, Philip; Compston, Alastair; Robberecht, Wim; Dubois, Bénédicte; van den Berg, Leonard H; De Jager, Philip L; Veldink, Jan H; de Bakker, Paul I W.

Hum Mol Genet ; 23(7): 1916-22, 2014 Apr 01.

Artículo en Inglés | MEDLINE | ID: mdl-24234648

6.

Grey Matter Etymology and the neuron(e).

Mehta, Arpan R; Mehta, Puja R; Anderson, Stephen P; MacKinnon, Barbara L H; Compston, Alastair.

Brain ; 143(1): 374-379, 2020 01 01.

Artículo en Inglés | MEDLINE | ID: mdl-31844876

7.

Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation.

Jones, Joanne L; Thompson, Sara A J; Loh, Priscilla; Davies, Jessica L; Tuohy, Orla C; Curry, Allison J; Azzopardi, Laura; Hill-Cawthorne, Grant; Fahey, Michael T; Compston, Alastair; Coles, Alasdair J.

Proc Natl Acad Sci U S A ; 110(50): 20200-5, 2013 Dec 10.

Artículo en Inglés | MEDLINE | ID: mdl-24282306

8.

Occasional essay: Multiple sclerosis in the digital age: 'seeing through a glass darkly'.

Compston, Alastair.

J Neurol Neurosurg Psychiatry ; 91(10): 1017-1023, 2020 10.

Artículo en Inglés | MEDLINE | ID: mdl-32709701

9.

From the Archives Muscular atrophy, after measles, in three members of a family. By J.A. Ormerod, M.D. Brain (October) 1884; 7 (part XXVII): 334-342; with The peroneal type of progressive muscular atrophy. By Howard H. Tooth, M.A, M.D., M.R.C.P (H.K Lewis, London). 1886; pages 44: with Critical Digests. Recent observations on progressive muscular atrophy. By H. H. Tooth, M.D. Brain (July) 1887; 10 (part XXXVIII): 243-253; with The peroneal form or leg-type of progressive muscular atrophy. By B. Sachs, M.D. (New York). Professor of Mental and Nervous Diseases in the New York Polyclinic, Brain 1890; 12: 447-459.

Compston, Alastair.

Brain ; 142(8): 2538-2543, 2019 08 01.

Artículo en Inglés | MEDLINE | ID: mdl-31292617

10.

Confounding underlies the apparent month of birth effect in multiple sclerosis.

Fiddes, Barnaby; Wason, James; Kemppinen, Anu; Ban, Maria; Compston, Alastair; Sawcer, Stephen.

Ann Neurol ; 73(6): 714-20, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23744589

11.

No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis.

Ban, Maria; Caillier, Stacy; Mero, Inger-Lise; Myhr, Kjell-Morten; Celius, Elisabeth G; Aarseth, Jan; Torkildsen, Øivind; Harbo, Hanne F; Oksenberg, Jorge; Hauser, Stephen L; Sawcer, Stephen; Compston, Alastair.

Ann Neurol ; 73(3): 430-2, 2013 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-23444327

12.

Predicting autoimmunity after alemtuzumab treatment of multiple sclerosis.

Azzopardi, Laura; Thompson, Sara A J; Harding, Katherine E; Cossburn, Mark; Robertson, Neil; Compston, Alastair; Coles, Alasdair J; Jones, Joanne L.

J Neurol Neurosurg Psychiatry ; 85(7): 795-8, 2014 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-24368840

13.

Editorial.

Compston, Alastair.

Brain ; 141(6): 1577-1579, 2018 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-29800476

14.

From the Archives.

Compston, Alastair.

Brain ; 141(4): 1229-1233, 2018 04 01.

Artículo en Inglés | MEDLINE | ID: mdl-29596664

15.

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.

Lill, Christina M; Schjeide, Brit-Maren M; Graetz, Christine; Ban, Maria; Alcina, Antonio; Ortiz, Miguel A; Pérez, Jennifer; Damotte, Vincent; Booth, David; Lopez de Lapuente, Aitzkoa; Broer, Linda; Schilling, Marcel; Akkad, Denis A; Aktas, Orhan; Alloza, Iraide; Antigüedad, Alfredo; Arroyo, Rafa; Blaschke, Paul; Buttmann, Mathias; Chan, Andrew; Compston, Alastair; Cournu-Rebeix, Isabelle; Dörner, Thomas; Epplen, Joerg T; Fernández, Óscar; Gerdes, Lisa-Ann; Guillot-Noël, Léna; Hartung, Hans-Peter; Hoffjan, Sabine; Izquierdo, Guillermo; Kemppinen, Anu; Kroner, Antje; Kubisch, Christian; Kümpfel, Tania; Li, Shu-Chen; Lindenberger, Ulman; Lohse, Peter; Lubetzki, Catherine; Luessi, Felix; Malhotra, Sunny; Mescheriakova, Julia; Montalban, Xavier; Papeix, Caroline; Paredes, Lidia F; Rieckmann, Peter; Steinhagen-Thiessen, Elisabeth; Winkelmann, Alexander; Zettl, Uwe K; Hintzen, Rogier; Vandenbroeck, Koen.

Brain ; 136(Pt 6): 1778-82, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23739915

16.

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex.

Zuvich, Rebecca L; Bush, William S; McCauley, Jacob L; Beecham, Ashley H; De Jager, Philip L; Ivinson, Adrian J; Compston, Alastair; Hafler, David A; Hauser, Stephen L; Sawcer, Stephen J; Pericak-Vance, Margaret A; Barcellos, Lisa F; Mortlock, Douglas P; Haines, Jonathan L.

Hum Mol Genet ; 20(17): 3517-24, 2011 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-21653641

17.

Magnetization transfer imaging in multiple sclerosis treated with alemtuzumab.

Button, Tom; Altmann, Dan; Tozer, Dan; Dalton, Catherine; Hunter, Kelvin; Compston, Alastair; Coles, Alasdair; Miller, David.

Mult Scler ; 19(2): 241-4, 2013 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22492133

18.

Progressive atrophy of the globus pallidus (primary atrophy of the pallidal system). A system disease of the paralysis agitans type, characterized by atrophy of the motor cells of the corpus striatum. A contribution to the function of the corpus striatum. By J. Ramsay Hunt MD, New York. Brain 1917; 40: 58-148.

Compston, Alastair.

Brain ; 140(6): 1808-1813, 2017 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-28430875

19.

The evolution of consciousness. Together with a diagram illustrating certain homologies in the nervous system. By W.H.B. Stoddart MD MRCP. Brain 1903; 26: 432-439. With The structure of consciousness by Michael Polanyi. Brain 1965; 88: 799-810.

Compston, Alastair.

Brain ; 140(9): 2511-2515, 2017 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-29050404

20.

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis.

Bronson, Paola G; Caillier, Stacy; Ramsay, Patricia P; McCauley, Jacob L; Zuvich, Rebecca L; De Jager, Philip L; Rioux, John D; Ivinson, Adrian J; Compston, Alastair; Hafler, David A; Sawcer, Stephen J; Pericak-Vance, Margaret A; Haines, Jonathan L; Hauser, Stephen L; Oksenberg, Jorge R; Barcellos, Lisa F.

Hum Mol Genet ; 19(11): 2331-40, 2010 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-20211854

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Multiple sclerosis risk variants alter expression of co-stimulatory genes in B cells.

Negligible impact of rare autoimmune-locus coding-region variants on missing heritability.

Reply: The etymology of 'neurology', redux: early use of the term by Jean Riolan the Younger (1610).

Neuronal expression of pathological tau accelerates oligodendrocyte progenitor cell differentiation.

No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis.

Grey Matter Etymology and the neuron(e).

Human autoimmunity after lymphocyte depletion is caused by homeostatic T-cell proliferation.

Occasional essay: Multiple sclerosis in the digital age: 'seeing through a glass darkly'.

Confounding underlies the apparent month of birth effect in multiple sclerosis.

No evidence of association between mutant alleles of the CYP27B1 gene and multiple sclerosis.

Predicting autoimmunity after alemtuzumab treatment of multiple sclerosis.

Editorial.

From the Archives.

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis.

Interrogating the complex role of chromosome 16p13.13 in multiple sclerosis susceptibility: independent genetic signals in the CIITA-CLEC16A-SOCS1 gene complex.

Magnetization transfer imaging in multiple sclerosis treated with alemtuzumab.

The evolution of consciousness. Together with a diagram illustrating certain homologies in the nervous system. By W.H.B. Stoddart MD MRCP. Brain 1903; 26: 432-439. With The structure of consciousness by Michael Polanyi. Brain 1965; 88: 799-810.

CIITA variation in the presence of HLA-DRB1*1501 increases risk for multiple sclerosis.