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1.
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase.
J Med Chem
; 50(8): 1727-30, 2007 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-17361995
2.
In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
J Med Chem
; 48(6): 1984-2008, 2005 Mar 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-15771442
3.
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.
J Med Chem
; 46(18): 3865-76, 2003 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-12930148
4.
A novel, potent dual inhibitor of the leukocyte proteases cathepsin G and chymase: molecular mechanisms and anti-inflammatory activity in vivo.
J Biol Chem
; 280(18): 18001-7, 2005 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-15741158
5.
Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design.
J Am Chem Soc
; 124(15): 3810-1, 2002 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-11942800
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