Detalles de la búsqueda
1.
Depolymerization of SUMO chains induces slender to stumpy differentiation in T. brucei bloodstream parasites.
PLoS Pathog
; 20(4): e1012166, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38635823
2.
A Brucella spp. Protease Inhibitor Limits Antigen Lysosomal Proteolysis, Increases Cross-Presentation, and Enhances CD8+ T Cell Responses.
J Immunol
; 196(10): 4014-29, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27084100
3.
Targeting Stat3 induces senescence in tumor cells and elicits prophylactic and therapeutic immune responses against breast cancer growth mediated by NK cells and CD4+ T cells.
J Immunol
; 189(3): 1162-72, 2012 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22753933
4.
A Gamma-adapted subunit vaccine induces broadly neutralizing antibodies against SARS-CoV-2 variants and protects mice from infection.
Nat Commun
; 15(1): 997, 2024 Feb 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-38307851
5.
Brucella abortus induces TNF-α-dependent astroglial MMP-9 secretion through mitogen-activated protein kinases.
J Neuroinflammation
; 10: 47, 2013 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-23587438
6.
Safety and immunogenicity of a SARS-CoV-2 Gamma variant RBD-based protein adjuvanted vaccine used as booster in healthy adults.
Nat Commun
; 14(1): 4551, 2023 07 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-37507392
7.
The protein moiety of Brucella abortus outer membrane protein 16 is a new bacterial pathogen-associated molecular pattern that activates dendritic cells in vivo, induces a Th1 immune response, and is a promising self-adjuvanting vaccine against systemic and oral acquired brucellosis.
J Immunol
; 184(9): 5200-12, 2010 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20351187
8.
A disordered region retains the full protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of the oral vaccine adjuvant U-Omp19.
Comput Struct Biotechnol J
; 20: 5098-5114, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36187929
9.
A Novel Bacterial Protease Inhibitor Adjuvant in RBD-Based COVID-19 Vaccine Formulations Containing Alum Increases Neutralizing Antibodies, Specific Germinal Center B Cells and Confers Protection Against SARS-CoV-2 Infection in Mice.
Front Immunol
; 13: 844837, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35296091
10.
U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge.
Vaccine
; 38(32): 5027-5035, 2020 07 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32536545
11.
Immunization with recombinant Brucella species outer membrane protein Omp16 or Omp19 in adjuvant induces specific CD4+ and CD8+ T cells as well as systemic and oral protection against Brucella abortus infection.
Infect Immun
; 77(1): 436-45, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18981242
12.
Oral co-administration of a bacterial protease inhibitor in the vaccine formulation increases antigen delivery at the intestinal epithelial barrier.
J Control Release
; 293: 158-171, 2019 01 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30496771
13.
Omp19 Enables Brucella abortus to Evade the Antimicrobial Activity From Host's Proteolytic Defense System.
Front Immunol
; 10: 1436, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31297115
14.
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice.
Front Immunol
; 8: 171, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28261222
15.
Brucella abortus Omp19 recombinant protein subcutaneously co-delivered with an antigen enhances antigen-specific T helper 1 memory responses and induces protection against parasite challenge.
Vaccine
; 34(4): 430-437, 2016 Jan 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-26707377
16.
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses.
J Control Release
; 220(Pt A): 18-28, 2015 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-26456256
17.
Unlipidated outer membrane protein Omp16 (U-Omp16) from Brucella spp. as nasal adjuvant induces a Th1 immune response and modulates the Th2 allergic response to cow's milk proteins.
PLoS One
; 8(7): e69438, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23861971
18.
Brucella abortus induces apoptosis of human T lymphocytes.
Microbes Infect
; 14(7-8): 639-50, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22387699
19.
Brucella abortus inhibits IFN-γ-induced FcγRI expression and FcγRI-restricted phagocytosis via toll-like receptor 2 on human monocytes/macrophages.
Microbes Infect
; 13(3): 239-50, 2011 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-21070860
20.
An oral vaccine based on U-Omp19 induces protection against B. abortus mucosal challenge by inducing an adaptive IL-17 immune response in mice.
PLoS One
; 6(1): e16203, 2011 Jan 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-21264260