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1.
Binding of common organic UV-filters to the thyroid hormone transport protein transthyretin using in vitro and in silico studies: Potential implications in health.
Environ Res
; 217: 114836, 2023 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36400222
2.
An Assay for Screening Potential Drug Candidates for Alzheimer's Disease That Act as Chaperones of the Transthyretin and Amyloid-ß Peptides Interaction.
Chemistry
; 26(72): 17462-17469, 2020 Dec 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32761825
3.
Optimization of kinetic stabilizers of tetrameric transthyretin: A prospective ligand efficiency-guided approach.
Bioorg Med Chem
; 28(23): 115794, 2020 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33091848
4.
Preparative Scale Production of Recombinant Human Transthyretin for Biophysical Studies of Protein-Ligand and Protein-Protein Interactions.
Int J Mol Sci
; 21(24)2020 Dec 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33348885
5.
Undiscovered Roles for Transthyretin: From a Transporter Protein to a New Therapeutic Target for Alzheimer's Disease.
Int J Mol Sci
; 21(6)2020 Mar 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-32197355
6.
Repurposing Benzbromarone for Familial Amyloid Polyneuropathy: A New Transthyretin Tetramer Stabilizer.
Int J Mol Sci
; 21(19)2020 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32998442
7.
Targeting transthyretin in Alzheimer's disease: Drug discovery of small-molecule chaperones as disease-modifying drug candidates for Alzheimer's disease.
Eur J Med Chem
; 226: 113847, 2021 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34555615
8.
Calorimetric Studies of Binary and Ternary Molecular Interactions between Transthyretin, Aß Peptides, and Small-Molecule Chaperones toward an Alternative Strategy for Alzheimer's Disease Drug Discovery.
J Med Chem
; 63(6): 3205-3214, 2020 03 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32124607
9.
Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-ß Formation in a Transgenic Mouse Model of Alzheimer's Disease: A Longitudinal in vivo Molecular Imaging Study1.
J Alzheimers Dis
; 77(1): 99-112, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32804152
10.
Radiochemical examination of transthyretin (TTR) brain penetration assisted by iododiflunisal, a TTR tetramer stabilizer and a new candidate drug for AD.
Sci Rep
; 9(1): 13672, 2019 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-31541162
11.
Insights on the Interaction between Transthyretin and Aß in Solution. A Saturation Transfer Difference (STD) NMR Analysis of the Role of Iododiflunisal.
J Med Chem
; 60(13): 5749-5758, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28587455
12.
Modulation of the fibrillogenesis inhibition properties of two transthyretin ligands by halogenation.
J Med Chem
; 56(22): 9110-21, 2013 Nov 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24147937
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