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1.
Effect of undermethylation on mRNA cytoplasmic appearance and half-life.
Mol Cell Biol
; 4(3): 538-43, 1984 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-6201720
2.
Biochemical and growth inhibitory effects of the erythro and threo isomers of gamma-fluoromethotrexate, a methotrexate analogue defective in polyglutamylation.
Cancer Res
; 49(16): 4517-25, 1989 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-2472880
3.
Stable multisubstrate adducts as enzyme inhibitors. Potent inhibition of ornithine decarboxylase by N-(5'-phosphopyridoxyl)-ornithine.
Biochim Biophys Acta
; 403(1): 197-207, 1975 Sep 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-1174545
4.
Aldehyde and phosphinate analogs of glutathione and glutathionylspermidine: potent, selective binding inhibitors of the E. coli bifunctional glutathionylspermidine synthetase/amidase.
Chem Biol
; 4(11): 859-66, 1997 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-9384533
5.
Use of aminopropyltransferase inhibitors and of non-metabolizable analogs to study polyamine regulation and function.
Int J Biochem Cell Biol
; 27(5): 425-42, 1995 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-7641073
6.
Inhibition of bacterial aminopropyltransferases by S-adenosyl-1,8-diamino-3-thiooctane and by dicyclohexylamine.
FEBS Lett
; 155(2): 192-6, 1983 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-6406265
7.
Stereospecific synthesis of (R)- and (S)-S-adenosyl-1,8-diamino-3-thiooctane, a potent inhibitor of polyamine biosynthesis. Comparison of asymmetric induction vs enantiomeric synthesis.
J Med Chem
; 34(7): 2094-101, 1991 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-2066981
8.
Analogues of S-adenosylhomocysteine as potential inhibitors of biological transmethylation. Synthesis of analogues with modifications at the 5'-thioether linkage.
J Med Chem
; 19(5): 684-91, 1976 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-1271409
9.
Synthesis and evaluation of some stable multisubstrate adducts as specific inhibitors of spermidine synthase.
J Med Chem
; 24(11): 1277-84, 1981 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-7310803
10.
Synthesis and biological evaluation of DL-4,4-difluoroglutamic acid and DL-gamma,gamma-difluoromethotrexate.
J Med Chem
; 39(1): 66-72, 1996 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-8568828
11.
alpha-Methyl polyamines: metabolically stable spermidine and spermine mimics capable of supporting growth in cells depleted of polyamines.
J Med Chem
; 35(4): 724-34, 1992 Feb 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-1542099
12.
Synthesis and biochemical evaluation of adenosylspermidine, a nucleoside-polyamine adduct inhibitor of spermidine synthase.
J Med Chem
; 38(14): 2714-27, 1995 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-7629810
13.
Polyamine biosynthesis in rat prostate. Substrate and inhibitor properties of 7-deaza analogues of decarboxylated S-adenosylmethionine and 5'-methylthioadenosine.
J Med Chem
; 20(4): 500-5, 1977 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-850235
14.
Synthesis and evaluation of some stable multisubstrate adducts as inhibitors of catechol O-methyltransferase.
J Med Chem
; 24(11): 1271-7, 1981 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-7310802
15.
Synthesis and biological evaluation of N alpha-(4-amino-4-deoxy-10-methylpteroyl)-DL-4,4-difluoroornithine.
J Med Chem
; 39(13): 2536-40, 1996 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-8691451
16.
Design, synthesis, and biochemical evaluation of phosphonate and phosphonamidate analogs of glutathionylspermidine as inhibitors of glutathionylspermidine synthetase/amidase from Escherichia coli.
J Med Chem
; 40(23): 3842-50, 1997 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-9371250
17.
Synthesis of N-[N-(4-deoxy-4-amino-10-methylpteroyl)-4-fluoroglutamyl]- gamma-glutamate, an unusual substrate for folylpoly-gamma-glutamate synthetase and gamma-glutamyl hydrolase.
J Med Chem
; 33(3): 1022-7, 1990 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-2308134
18.
Synthesis and biological evaluation of S-adenosyl-1,12-diamino-3-thio-9-azadodecane, a multisubstrate adduct inhibitor of spermine synthase.
J Med Chem
; 32(6): 1300-7, 1989 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-2724300
19.
Synthesis and biological activity of folic acid and methotrexate analogues containing L-threo-(2S,4S)-4-fluoroglutamic acid and DL-3,3-difluoroglutamic acid.
J Med Chem
; 39(1): 56-65, 1996 Jan 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-8568827
20.
Effect of N-(n-butyl)-1,3-diaminopropane on polyamine metabolism, cell growth and sensitivity to chloroethylating agents.
Biochem Pharmacol
; 46(4): 717-24, 1993 Aug 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-8395844