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1.
Phase 1 trial of IL-15 trans presentation blockade using humanized Mikß1 mAb in patients with T-cell large granular lymphocytic leukemia.
Blood
; 121(3): 476-84, 2013 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-23212516
2.
IL-15 administered by continuous infusion to rhesus macaques induces massive expansion of CD8+ T effector memory population in peripheral blood.
Blood
; 118(26): 6845-8, 2011 Dec 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22067383
3.
Safety (toxicity), pharmacokinetics, immunogenicity, and impact on elements of the normal immune system of recombinant human IL-15 in rhesus macaques.
Blood
; 117(18): 4787-95, 2011 May 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-21385847
4.
Purification of clinical-grade disulfide stabilized antibody fragment variable--Pseudomonas exotoxin conjugate (dsFv-PE38) expressed in Escherichia coli.
Appl Microbiol Biotechnol
; 97(2): 621-32, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-22890777
5.
Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates.
Blood
; 116(17): 3238-48, 2010 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-20631381
6.
IL15 by Continuous Intravenous Infusion to Adult Patients with Solid Tumors in a Phase I Trial Induced Dramatic NK-Cell Subset Expansion.
Clin Cancer Res
; 25(16): 4945-4954, 2019 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31142503
7.
Mammalian cell transient expression, non-affinity purification, and characterization of human recombinant IGFBP7, an IGF-1 targeting therapeutic protein.
Int Immunopharmacol
; 29(2): 476-487, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26474694
8.
Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer.
J Clin Oncol
; 33(1): 74-82, 2015 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25403209
9.
Clinical manufacturing of recombinant human interleukin 15. I. Production cell line development and protein expression in E. coli with stop codon optimization.
Biotechnol Prog
; 28(2): 497-507, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22162520
10.
MTS dye based colorimetric CTLL-2 cell proliferation assay for product release and stability monitoring of interleukin-15: assay qualification, standardization and statistical analysis.
J Immunol Methods
; 348(1-2): 83-94, 2009 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-19646987
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