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1.
Identification of small molecules and related targets that modulate tau pathology in a seeded primary neuron model.
J Biol Chem
; 299(7): 104876, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37269953
2.
Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays.
J Biol Chem
; 295(12): 4001-4013, 2020 03 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32034092
3.
The Dynamics and Turnover of Tau Aggregates in Cultured Cells: INSIGHTS INTO THERAPIES FOR TAUOPATHIES.
J Biol Chem
; 291(25): 13175-93, 2016 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-27129267
4.
Aminothienopyridazines and methylene blue affect Tau fibrillization via cysteine oxidation.
J Biol Chem
; 288(16): 11024-37, 2013 Apr 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-23443659
5.
Aminothienopyridazine inhibitors of tau aggregation: evaluation of structure-activity relationship leads to selection of candidates with desirable in vivo properties.
Bioorg Med Chem
; 20(14): 4451-61, 2012 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22717239
6.
Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screening.
Biochemistry
; 48(32): 7732-45, 2009 Aug 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-19580328
7.
Inhibition of tau fibrillization by oleocanthal via reaction with the amino groups of tau.
J Neurochem
; 110(4): 1339-51, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19549281
8.
Case mix, outcome and activity for patients with severe acute kidney injury during the first 24 hours after admission to an adult, general critical care unit: application of predictive models from a secondary analysis of the ICNARC Case Mix Programme database.
Crit Care
; 12 Suppl 1: S2, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-19105800
9.
Ventriculo-peritoneal shunt infection in a patient on hemodialysis.
Hemodial Int
; 12(3): 319-21, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18638086
10.
Case mix, outcome and activity for patients admitted to intensive care units requiring chronic renal dialysis: a secondary analysis of the ICNARC Case Mix Programme Database.
Crit Care
; 11(2): R50, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-17451605
11.
Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care.
Front Neurol
; 10: 1116, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31781016
12.
Developing an online, modular, active learning training program for behavioral activation.
Psychotherapy (Chic)
; 50(2): 256-65, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23398030
13.
Design, synthesis, and biological evaluation of 1-phenylpyrazolo[3,4-e]pyrrolo[3,4-g]indolizine-4,6(1H,5H)-diones as new glycogen synthase kinase-3ß inhibitors.
J Med Chem
; 56(24): 10066-78, 2013 Dec 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24295046
14.
Tau-directed drug discovery for Alzheimer's disease and related tauopathies: a focus on tau assembly inhibitors.
Exp Neurol
; 223(2): 304-10, 2010 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19744482
15.
Discovery of brain-penetrant, orally bioavailable aminothienopyridazine inhibitors of tau aggregation.
J Med Chem
; 53(9): 3739-47, 2010 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-20392114
16.
Surviving and thriving in the early years as a new consultant physician.
Clin Med (Lond)
; 4(2): 185-6, 2004.
Artículo
en Inglés
| MEDLINE | ID: mdl-15139743
17.
Lanthanum associated abnormal liver function tests in two patients on dialysis: a case report.
J Med Case Rep
; 3: 9321, 2009 Dec 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-20062750
18.
High throughput screening for small molecule inhibitors of heparin-induced tau fibril formation.
Biochem Biophys Res Commun
; 358(1): 1-6, 2007 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-17482143
19.
Biochemical and pathological characterization of frontotemporal dementia due to a Leu266Val mutation in microtubule-associated protein tau in an African American individual.
Acta Neuropathol
; 113(4): 471-9, 2007 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-17072625
20.
An English kindred with a novel recessive tauopathy and respiratory failure.
Ann Neurol
; 54(5): 682-6, 2003 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-14595660