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1.
Novel Structure-Driven Predict-to-Hit Strategy for PC Double Bond Positional Isomer Identification Based on Negative LC-MRM Analysis.
Anal Chem
; 2024 Feb 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38330201
2.
Safety, efficacy and pharmacokinetics of BPI-9016M in c-MET overexpression or MET exon 14 skipping mutation patients with locally advanced or metastatic non-small-cell lung cancer: a phase Ib study.
BMC Cancer
; 23(1): 331, 2023 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37041472
3.
Comprehensive lipid profiling of plasma in patients with benign breast tumor and breast cancer reveals novel biomarkers.
Anal Bioanal Chem
; 407(17): 5065-77, 2015 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-25651902
4.
Ganoderma lucidum ethanol extracts ameliorate hepatic fibrosis and promote the communication between metabolites and gut microbiota g_Ruminococcus through the NF-κB and TGF-ß1/Smads pathways.
J Ethnopharmacol
; 322: 117656, 2024 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38154526
5.
Development and validation of a deep learning-based model to predict response and survival of T790M mutant non-small cell lung cancer patients in early clinical phase trials using electronic medical record and pharmacokinetic data.
Transl Lung Cancer Res
; 13(4): 706-720, 2024 Apr 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-38736496
6.
Development and validation of two bioanalysis methods for the determination of etimicin in human serum and urine by liquid chromatography-tandem mass spectrometry: Applications to a human pharmacokinetic and breakpoint study.
Front Pharmacol
; 14: 1076046, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36713844
7.
Liquid chromatography-tandem mass spectrometry methods for quantification of roxadustat (FG-4592) in human plasma and urine and the applications in two clinical pharmacokinetic studies.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1203: 123274, 2022 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35662878
8.
Development of an LC-MS/MS method for quantifying ASK120067, a novel mutant-selective inhibitor of the epidermal growth factor receptor (EGFR) as well as its main metabolite in human plasma and its application in a pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1162: 122488, 2021 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33360679
9.
Development of a rapid and sensitive UPLC-MS/MS assay for simultaneous quantitation of Vorolanib and its metabolite in human plasma and application to a pharmacokinetics study.
J Pharm Biomed Anal
; 199: 114034, 2021 May 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-33774456
10.
Simultaneous determination of indapamide, perindopril and its active metabolite perindoprilat in human plasma using UPLC-MS/MS method.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1169: 122585, 2021 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33706186
11.
First-in-human phase I study of BPI-9016M, a dual MET/Axl inhibitor, in patients with non-small cell lung cancer.
J Hematol Oncol
; 13(1): 6, 2020 01 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-31948451
12.
Prevalence, phylogenetic and evolutionary analysis of porcine deltacoronavirus in Henan province, China.
Prev Vet Med
; 166: 8-15, 2019 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30935509
13.
Development of a quantitative method for four photocyanine isomers using differential ion mobility and tandem mass spectrometry and its application in a preliminary pharmacokinetics investigation.
J Chromatogr A
; 1577: 109-119, 2018 Nov 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-30274691
14.
Simultaneous determination of a novel c-Met/AXL dual-target small-molecule inhibitor BPI-9016M and its metabolites in human plasma by liquid chromatography-tandem mass spectrometry: Application in a pharmacokinetic study in Chinese advanced solid tumor patients.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1068-1069: 33-40, 2017 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29028616
15.
Simultaneous determination of roflumilast and its metabolite in human plasma by LC-MS/MS: Application for a pharmacokinetic study.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1029-1030: 60-67, 2016 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27423044
16.
A not-stop-flow online normal-/reversed-phase two-dimensional liquid chromatography-quadrupole time-of-flight mass spectrometry method for comprehensive lipid profiling of human plasma from atherosclerosis patients.
J Chromatogr A
; 1372C: 110-119, 2014 12 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-25465009
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