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1.
Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.
FASEB J
; 18(9): 959-61, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15059979
2.
Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-cells.
Endocrinology
; 145(6): 2845-57, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15001544
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