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1.
Potent noncovalent thrombin inhibitors that utilize the unique amino acid D-dicyclohexylalanine in the P3 position. Implications on oral bioavailability and antithrombotic efficacy.
J Med Chem
; 40(11): 1565-9, 1997 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-9171866
2.
Discovery of a novel, selective, and orally bioavailable class of thrombin inhibitors incorporating aminopyridyl moieties at the P1 position.
J Med Chem
; 40(23): 3726-33, 1997 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-9371237
3.
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position.
J Med Chem
; 41(17): 3210-9, 1998 Aug 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-9703466
4.
Synthesis of a series of potent and orally bioavailable thrombin inhibitors that utilize 3,3-disubstituted propionic acid derivatives in the P3 position.
J Med Chem
; 40(22): 3687-93, 1997 Oct 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-9357536
5.
Design and synthesis of potent, selective, and orally bioavailable tetrasubstituted imidazole inhibitors of p38 mitogen-activated protein kinase.
J Med Chem
; 42(12): 2180-90, 1999 Jun 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-10377223
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