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1.
Discovery of Small-Molecule VapC1 Nuclease Inhibitors by Virtual Screening and Scaffold Hopping from an Atomic Structure Revealing Protein-Protein Interactions with a Native VapB1 Inhibitor.
J Chem Inf Model
; 62(5): 1249-1258, 2022 03 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35103473
2.
Functional whole genome screen of nutrient-starved Mycobacterium tuberculosis identifies genes involved in antibiotic tolerance.
bioRxiv
; 2023 Apr 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37090629
3.
Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance.
Microorganisms
; 11(9)2023 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37764112
4.
An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis.
Front Immunol
; 13: 972266, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36189260
5.
Targeting the Mycobacterium tuberculosis Stringent Response as a Strategy for Shortening Tuberculosis Treatment.
Front Microbiol
; 12: 744167, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34690990
6.
Genetic Determinants of Intrinsic Antibiotic Tolerance in Mycobacterium avium.
Microbiol Spectr
; 9(2): e0024621, 2021 10 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34523947
7.
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell Rep
; 35(4): 109040, 2021 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-33910017
8.
Role of Cell Surface Hydrophobicity in the Pathogenesis of Medically-Significant Fungi.
Front Cell Infect Microbiol
; 10: 594973, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33569354
9.
Variation in Cell Surface Hydrophobicity among Cryptococcus neoformans Strains Influences Interactions with Amoebas.
mSphere
; 5(2)2020 04 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-32350094
10.
A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.
Sci Rep
; 10(1): 4203, 2020 03 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32144367
11.
Keeping It Clean: The Cell Culture Quality Control Experience at the National Center for Advancing Translational Sciences.
SLAS Discov
; 25(5): 491-497, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32233736
12.
Design, Synthesis, and Biological Evaluation of Quinazolin-4-one-Based Hydroxamic Acids as Dual PI3K/HDAC Inhibitors.
J Med Chem
; 63(8): 4256-4292, 2020 04 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-32212730
13.
Bioactivity and composition of a preserved connective tissue matrix derived from human placental tissue.
J Biomed Mater Res B Appl Biomater
; 106(8): 2731-2740, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-29437272
14.
Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.
PLoS One
; 13(5): e0197292, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29763427
15.
Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular Activity.
J Med Chem
; 61(11): 4883-4903, 2018 06 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29767973
16.
Author Correction: A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells.
Sci Rep
; 12(1): 17185, 2022 Oct 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36229506
17.
A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity.
PLoS One
; 12(1): e0170937, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28129349
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