Detalles de la búsqueda
1.
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity.
Bioconjug Chem
; 33(10): 1860-1866, 2022 10 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-36106863
2.
Glucocorticoid receptor modulators CpdX and CpdX-D3 exhibit the same in vivo antiinflammatory activities as synthetic glucocorticoids.
Proc Natl Acad Sci U S A
; 116(28): 14191-14199, 2019 07 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31227605
3.
Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model.
Molecules
; 26(2)2021 Jan 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450992
4.
Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.
Biochim Biophys Acta Mol Cell Res
; 1864(6): 1018-1027, 2017 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-28109792
5.
Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice.
Neuroimmunomodulation
; 24(6): 331-340, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29680839
6.
Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.
Neuroimmunomodulation
; 23(5-6): 261-270, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28030866
7.
Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.
J Immunol
; 192(4): 1847-54, 2014 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24453258
8.
Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation.
Respir Res
; 16: 77, 2015 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-26112287
9.
An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice.
J Biol Chem
; 288(17): 11865-76, 2013 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23449983
10.
NMR HRMAS spectroscopy of lung biopsy samples: Comparison study between human, pig, rat, and mouse metabolomics.
Magn Reson Med
; 71(1): 35-43, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23412987
11.
A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma.
J Immunol
; 188(7): 3478-87, 2012 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22393156
12.
Multitarget µ-Opioid Receptor AgonistsâNeuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects.
J Med Chem
; 67(9): 7603-7619, 2024 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-38687204
13.
Targeted Anticancer Agent with Original Mode of Action Prepared by Supramolecular Assembly of Antibody Oligonucleotide Conjugates and Cationic Nanoparticles.
Pharmaceutics
; 15(6)2023 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-37376091
14.
Context-dependent function of TSLP and IL-1ß in skin allergic sensitization and atopic march.
Nat Commun
; 13(1): 4703, 2022 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36050303
15.
Eosinophils in Asthma Models to House Dust Mite for Drug Development.
Methods Mol Biol
; 2241: 75-87, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33486729
16.
An Autophagy Modulator Peptide Prevents Lung Function Decrease and Corrects Established Inflammation in Murine Models of Airway Allergy.
Cells
; 10(9)2021 09 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-34572117
17.
A Selective Neutraligand for CXCL12/SDF-1α With Beneficial Regulatory Functions in MRL/Lpr Lupus Prone Mice.
Front Pharmacol
; 12: 752194, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34744730
18.
Overexpression of the MSK1 Kinase in Patients With Chronic Lung Allograft Dysfunction and Its Confirmed Role in a Murine Model.
Transplantation
; 105(6): 1212-1224, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33560725
19.
A near-infrared fluorogenic dimer enables background-free imaging of endogenous GPCRs in living mice.
Chem Sci
; 11(26): 6824-6829, 2020 Jul 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33033597
20.
Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.
Eur J Med Chem
; 147: 163-182, 2018 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29432948