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1.
Limited sampling strategy and population pharmacokinetic model of mycophenolic acid in pediatric patients with systemic lupus erythematosus: application of a double gamma absorption model with SAEM algorithm.
Eur J Clin Pharmacol
; 80(1): 83-92, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37897528
2.
Towards Precision Dosing of Clozapine in Schizophrenia: External Evaluation of Population Pharmacokinetic Models and Bayesian Forecasting.
Ther Drug Monit
; 44(5): 674-682, 2022 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35385439
3.
Stacked Generalization with Applicability Domain Outperforms Simple QSAR on in Vitro Toxicological Data.
J Chem Inf Model
; 59(4): 1486-1496, 2019 04 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-30735402
4.
External Evaluation of Population Pharmacokinetics Models of Lithium in the Bipolar Population.
Pharmaceuticals (Basel)
; 16(11)2023 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38004492
5.
Combining pharmacokinetic and electrophysiological models for early prediction of drug-induced arrhythmogenicity.
Comput Methods Programs Biomed
; 242: 107860, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37844488
6.
Hypoxia signalling in cancer and approaches to enforce tumour regression.
Nature
; 441(7092): 437-43, 2006 May 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-16724055
7.
Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway.
J Cell Physiol
; 218(1): 167-74, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-18781596
8.
Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway.
J Theor Biol
; 259(2): 304-16, 2009 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-19298827
9.
The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
Cancer Res
; 66(7): 3688-98, 2006 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16585195
10.
HIF-1: master and commander of the hypoxic world. A pharmacological approach to its regulation by siRNAs.
Biochem Pharmacol
; 68(6): 971-80, 2004 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15313390
11.
The HIF-1-inducible lysyl oxidase activates HIF-1 via the Akt pathway in a positive regulation loop and synergizes with HIF-1 in promoting tumor cell growth.
Cancer Res
; 71(5): 1647-57, 2011 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-21239473
12.
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.
Cancer Res
; 69(1): 358-68, 2009 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19118021
13.
A dialogue between the hypoxia-inducible factor and the tumor microenvironment.
Cancer Microenviron
; 1(1): 53-68, 2008 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-19308685
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