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1.
Effects of Extended-Release Nicotinic Acid on Apolipoprotein (a) Kinetics in Hypertriglyceridemic Patients.
Arterioscler Thromb Vasc Biol
; 35(9): 2042-7, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26160958
2.
A Randomized, Placebo-Controlled Trial to Assess the Effects of 8 Weeks of Administration of GSK256073, a Selective GPR109A Agonist, on High-Density Lipoprotein Cholesterol in Subjects With Dyslipidemia.
Clin Pharmacol Drug Dev
; 8(7): 871-883, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31268250
3.
Discovery of 4-{4-[3-(pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): a potent, selective, and orally active transforming growth factor-beta type I receptor inhibitor.
J Med Chem
; 49(7): 2210-21, 2006 Apr 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-16570917
4.
Inhibition of ALK5 as a new approach to treat liver fibrotic diseases.
Drug News Perspect
; 19(2): 85-90, 2006 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-16628263
5.
Inhibition of TGF-beta signaling by an ALK5 inhibitor protects rats from dimethylnitrosamine-induced liver fibrosis.
Br J Pharmacol
; 145(2): 166-77, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15723089
6.
GSK256073 acutely regulates NEFA levels via HCA2 agonism but does not achieve durable glycaemic control in type 2 diabetes. A randomised trial.
Eur J Pharmacol
; 755: 95-101, 2015 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25773496
7.
Discovery and characterization of GSK256073, a non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) agonist.
Eur J Pharmacol
; 756: 1-7, 2015 Jun 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-25773497
8.
Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression.
Int J Radiat Oncol Biol Phys
; 56(2): 561-72, 2003 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12738334
9.
The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 1: 5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione analogues.
J Med Chem
; 46(21): 4525-32, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521414
10.
The discovery of tadalafil: a novel and highly selective PDE5 inhibitor. 2: 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione analogues.
J Med Chem
; 46(21): 4533-42, 2003 Oct 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-14521415
11.
Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors.
J Med Chem
; 47(18): 4494-506, 2004 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-15317461
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