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1.
Development of a screening assay to measure the loss of antibacterial activity in the presence of proteins: its use in optimizing compound structure.
J Biomol Screen
; 8(5): 555-8, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14567782
2.
Synthesis and evaluation of unsaturated caprolactams as interleukin-1beta converting enzyme (ICE) inhibitors.
Bioorg Med Chem
; 15(3): 1311-22, 2007 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17127070
3.
Synthesis and evaluation of thiazepines as interleukin-1beta converting enzyme (ICE) inhibitors.
Bioorg Med Chem Lett
; 16(18): 4728-32, 2006 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16870441
4.
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.
Bioorg Med Chem Lett
; 16(21): 5659-63, 2006 Nov 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16919947
5.
Synthesis and evaluation of novel 1-(2-acylhydrazinocarbonyl)-cycloalkyl carboxamides as interleukin-1beta converting enzyme (ICE) inhibitors.
Bioorg Med Chem Lett
; 16(16): 4233-6, 2006 Aug 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16782334
6.
Synthesis and evaluation of novel 8,5-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme (ICE) inhibitors.
Bioorg Med Chem
; 14(23): 7880-92, 2006 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16908171
7.
Synthesis and evaluation of tricyclic pyrrolopyrimidinones as dipeptide mimetics: inhibition of interleukin-1beta-converting enzyme.
Bioorg Med Chem Lett
; 15(19): 4322-6, 2005 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16046129
8.
Synthesis and evaluation of novel 8,6-fused bicyclic peptidomimetic compounds as interleukin-1beta converting enzyme inhibitors.
Bioorg Med Chem Lett
; 15(24): 5434-8, 2005 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16216507
9.
Discovery of novel conformationally restricted diazocan peptidomimetics as inhibitors of interleukin-1beta synthesis.
Bioorg Med Chem Lett
; 15(19): 4291-4, 2005 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16046125
10.
Interactions between penicillin-binding proteins (PBPs) and two novel classes of PBP inhibitors, arylalkylidene rhodanines and arylalkylidene iminothiazolidin-4-ones.
Antimicrob Agents Chemother
; 48(3): 961-9, 2004 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-14982790
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