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1.
Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening.
Bioorg Med Chem Lett
; 30(24): 127609, 2020 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33039562
2.
Expansion of a novel lead targeting M. tuberculosis DHFR as antitubercular agents.
Bioorg Med Chem
; 27(7): 1421-1429, 2019 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30827867
3.
Synthesis of 2,2,4-trimethyl-1,2-dihydroquinolinyl substituted 1,2,3-triazole derivatives: their evaluation as potential PDE 4B inhibitors possessing cytotoxic properties against cancer cells.
Bioorg Chem
; 53: 8-14, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24463218
4.
Spiro heterocycles as potential inhibitors of SIRT1: Pd/C-mediated synthesis of novel N-indolylmethyl spiroindoline-3,2'-quinazolines.
Bioorg Med Chem Lett
; 23(5): 1351-7, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23410798
5.
Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties.
Org Biomol Chem
; 11(19): 3103-7, 2013 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23575971
6.
Novel N-indolylmethyl substituted olanzapine derivatives: their design, synthesis and evaluation as PDE4B inhibitors.
Org Biomol Chem
; 11(13): 2075-9, 2013 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-23436140
7.
Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo.
Org Biomol Chem
; 11(39): 6680-5, 2013 Oct 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23986357
8.
Novel imidazophenoxazine-4-sulfonamides: their synthesis and evaluation as potential inhibitors of PDE4.
Bioorg Med Chem
; 21(7): 1952-63, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23415088
9.
Novel Diarylthioether Compounds as Agents for the Treatment of Chagas Disease.
J Med Chem
; 66(2): 1522-1542, 2023 01 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-36626662
10.
Pyrrolo[2,3-b]quinoxalines as inhibitors of firefly luciferase: their Cu-mediated synthesis and evaluation as false positives in a reporter gene assay.
Bioorg Med Chem Lett
; 22(20): 6433-41, 2012 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22981335
11.
A Review of the Biological Activities of Heterocyclic Compounds Comprising Oxadiazole Moieties.
Curr Top Med Chem
; 22(7): 578-599, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35114924
12.
2,4,5-Trisubstituted Thiazole: A Privileged Scaffold in Drug Design and Activity Improvement.
Curr Top Med Chem
; 20(28): 2535-2577, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32942975
13.
Discovery of Potent N-Ethylurea Pyrazole Derivatives as Dual Inhibitors of Trypanosoma brucei and Trypanosoma cruzi.
ACS Med Chem Lett
; 11(3): 278-285, 2020 Mar 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32184957
14.
Development of Benzenesulfonamide Derivatives as Potent Glutathione Transferase Omega-1 Inhibitors.
J Med Chem
; 63(6): 2894-2914, 2020 03 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-32105470
15.
Derivatives and Analogues of Resveratrol: Recent Advances in Structural Modification.
Mini Rev Med Chem
; 19(10): 809-825, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30686253
16.
Estrogen Receptor α (ERα)-targeting Compounds and Derivatives: Recent Advances in Structural Modification and Bioactivity.
Curr Top Med Chem
; 19(15): 1318-1337, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-31215379
17.
Substituted Pyridazin-3(2 H)-ones as Highly Potent and Biased Formyl Peptide Receptor Agonists.
J Med Chem
; 62(10): 5242-5248, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31038950
18.
Multifunctional Analogs of Kynurenic Acid for the Treatment of Alzheimer's Disease: Synthesis, Pharmacology, and Molecular Modeling Studies.
ACS Chem Neurosci
; 8(12): 2667-2675, 2017 12 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28825789
19.
Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons.
Eur J Med Chem
; 135: 110-116, 2017 Jul 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28441579
20.
Effect of the Biphenyl Neolignan Honokiol on Aß42-Induced Toxicity in Caenorhabditis elegans, Aß42 Fibrillation, Cholinesterase Activity, DPPH Radicals, and Iron(II) Chelation.
ACS Chem Neurosci
; 8(9): 1901-1912, 2017 09 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-28650631