Detalles de la búsqueda
1.
NLX-112, a highly selective 5-HT1A receptor biased agonist, does not exhibit misuse potential in male rats or macaques.
Neuropharmacology
; 210: 109025, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35276118
2.
NLX-101, a highly selective 5-HT1A receptor biased agonist, mediates antidepressant-like activity in rats via prefrontal cortex 5-HT1A receptors.
Behav Brain Res
; 401: 113082, 2021 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33358917
3.
The selective 5-HT1A receptor agonist, NLX-112, exerts anti-dyskinetic effects in MPTP-treated macaques.
Parkinsonism Relat Disord
; 78: 151-157, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32846366
4.
NLX-112, a highly selective 5-HT1A receptor agonist, mediates analgesia and antidepressant-like activity in rats via spinal cord and prefrontal cortex 5-HT1A receptors, respectively.
Brain Res
; 1688: 1-7, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29555239
5.
NLX-112, a highly selective 5-HT1A receptor agonist: Effects on body temperature and plasma corticosterone levels in rats.
Pharmacol Biochem Behav
; 165: 56-62, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29126856
6.
F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. III. Activity in models of cognition and negative symptoms.
Br J Pharmacol
; 151(2): 266-77, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17375085
7.
F15063, a compound with D2/D3 antagonist, 5-HT 1A agonist and D4 partial agonist properties. II. Activity in models of positive symptoms of schizophrenia.
Br J Pharmacol
; 151(2): 253-65, 2007 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-17375086
8.
SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficit.
Psychopharmacology (Berl)
; 181(1): 134-44, 2005 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-15830220
9.
NLX-112, a novel 5-HT1A receptor agonist for the treatment of L-DOPA-induced dyskinesia: Behavioral and neurochemical profile in rat.
Exp Neurol
; 271: 335-50, 2015 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-26037043
10.
Dopamine D3 receptor agonists produce similar decreases in body temperature and locomotor activity in D3 knock-out and wild-type mice.
Neuropharmacology
; 38(4): 555-65, 1999 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-10221759
11.
Dopamine D2 receptor knock-out mice are insensitive to the hypolocomotor and hypothermic effects of dopamine D2/D3 receptor agonists.
Neuropharmacology
; 38(9): 1389-96, 1999 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-10471093
12.
SSR181507, a putative atypical antipsychotic with dopamine D2 antagonist and 5-HT1A agonist activities: improvement of social interaction deficits induced by phencyclidine in rats.
Neuropharmacology
; 46(8): 1121-9, 2004 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15111019
13.
Discriminative stimulus effects of apomorphine and 7-OH-DPAT: a potential role for dopamine D3 receptors.
Psychopharmacology (Berl)
; 130(4): 387-95, 1997 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-9160856
14.
Behavioural effects in the rat of the putative dopamine D3 receptor agonist 7-OH-DPAT: comparison with quinpirole and apomorphine.
Psychopharmacology (Berl)
; 124(3): 231-40, 1996 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-8740044
15.
Potentiation of prepulse inhibition of the startle reflex in rats: pharmacological evaluation of the procedure as a model for detecting antipsychotic activity.
Psychopharmacology (Berl)
; 132(4): 366-74, 1997 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-9298514
16.
Intracranial self-stimulation under a progressive-ratio schedule in rats: effects of strength of stimulation, d-amphetamine, 7-OH-DPAT and haloperidol.
Psychopharmacology (Berl)
; 142(3): 221-9, 1999 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-10208313
17.
Tolerance to the reinforcing effects of cocaine in a progressive ratio paradigm.
Psychopharmacology (Berl)
; 116(3): 326-32, 1994 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-7892423
18.
What brain structures are active during emotions? Effects of brain stimulation elicited aversion on c-fos immunoreactivity and behavior.
Behav Brain Res
; 58(1-2): 9-18, 1993 Dec 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-8136052
19.
Haloperidol-induced catalepsy is absent in dopamine D(2), but maintained in dopamine D(3) receptor knock-out mice.
Eur J Pharmacol
; 391(1-2): 63-73, 2000 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-10720636
20.
Decreased locomotor activity after microinjection of dopamine D2/D3 receptor agonists and antagonists into lobule 9/10 of the cerebellum: a D3 receptor mediated effect?
Prog Neuropsychopharmacol Biol Psychiatry
; 24(1): 39-49, 2000 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-10659982