Detalles de la búsqueda
1.
Synthesis of an apionucleoside family and discovery of a prodrug with anti-HIV activity.
J Org Chem
; 79(11): 5097-112, 2014 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-24804575
2.
ProTides of N-(3-(5-(2'-deoxyuridine))prop-2-ynyl)octanamide as potential anti-tubercular and anti-viral agents.
Bioorg Med Chem
; 22(9): 2816-24, 2014 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24690527
3.
Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives.
Front Cell Dev Biol
; 11: 1247324, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37900280
4.
Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin.
Antimicrob Agents Chemother
; 56(5): 2604-11, 2012 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-22314523
5.
A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
J Infect Dis
; 201(4): 635-43, 2010 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20085496
6.
Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.
JCI Insight
; 6(7)2021 04 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33735112
7.
Application of the phosphoramidate ProTide approach to the antiviral drug ribavirin.
Bioorg Med Chem
; 18(7): 2748-55, 2010 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20207546
8.
2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743.
Bioorg Med Chem Lett
; 19(22): 6264-7, 2009 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19833513
9.
Alkenyl substituted bicyclic nucleoside analogues retain nanomolar potency against Varicella Zoster Virus.
Bioorg Med Chem
; 17(8): 3025-7, 2009 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19328697
10.
Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel.
J Med Chem
; 62(11): 5312-5329, 2019 06 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31083995
11.
Successful kinase bypass with new acyclovir phosphoramidate prodrugs.
Bioorg Med Chem Lett
; 18(15): 4364-7, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18614365
12.
Virtual Screening of Acyclovir Derivatives as Potential Antiviral Agents: Design, Synthesis, and Biological Evaluation of New Acyclic Nucleoside ProTides.
J Med Chem
; 60(18): 7876-7896, 2017 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-28829913
13.
d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity.
Front Cell Neurosci
; 11: 262, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28928635
14.
Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death.
JCI Insight
; 2(24)2017 12 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-29263311
15.
From ligand to complexes: inhibition of human immunodeficiency virus type 1 integrase by beta-diketo acid metal complexes.
J Med Chem
; 49(14): 4248-60, 2006 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-16821784
16.
Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues.
ChemistryOpen
; 5(3): 227-35, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27551659
17.
Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides.
Eur J Med Chem
; 70: 326-40, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24177359
18.
Synthesis and antiviral evaluation of α-L-2'-deoxythreofuranosyl nucleosides.
Eur J Med Chem
; 46(9): 3704-13, 2011 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-21664010
19.
Evaluation of novel phosphoramidate ProTides of the 2'-fluoro derivatives of a potent anti-varicella zoster virus bicyclic nucleoside analogue.
Antivir Chem Chemother
; 21(1): 15-31, 2010 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-21045257
20.
The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.
J Med Chem
; 52(17): 5520-30, 2009 Sep 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-19645484