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1.
Effects of levetiracetam, an antiepileptic drug, on memory impairments associated with aging and Alzheimer's disease in mice.
Neurobiol Learn Mem
; 102: 7-11, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23416036
2.
Mitochondrial dysfunction and accumulation of the ß-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice.
Neurobiol Dis
; 45(1): 417-24, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21933711
3.
Mitochondrial trafficking of APP and alpha synuclein: Relevance to mitochondrial dysfunction in Alzheimer's and Parkinson's diseases.
Biochim Biophys Acta
; 1802(1): 11-9, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19619643
4.
Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice.
J Neurochem
; 113(1): 248-61, 2010 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-20089133
5.
Genetic reductions of beta-site amyloid precursor protein-cleaving enzyme 1 and amyloid-beta ameliorate impairment of conditioned taste aversion memory in 5XFAD Alzheimer's disease model mice.
Eur J Neurosci
; 31(1): 110-8, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-20092558
6.
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.
J Neurosci
; 26(35): 9057-68, 2006 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-16943564
7.
Amyloid precursor protein and mitochondrial dysfunction in Alzheimer's disease.
Neuroscientist
; 13(6): 626-38, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17911214
8.
Mitochondrial translocation of amyloid precursor protein and its cleaved products: relevance to mitochondrial dysfunction in Alzheimer's disease.
Rev Neurosci
; 18(5): 343-54, 2007.
Artículo
en Inglés
| MEDLINE | ID: mdl-19544621
9.
Cognitive benefits of memantine in Alzheimer's 5XFAD model mice decline during advanced disease stages.
Pharmacol Biochem Behav
; 144: 60-6, 2016 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-26948858
10.
A combination Alzheimer's therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice.
Mol Brain
; 8: 19, 2015 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-25884928
11.
Beneficial effects of the ß-secretase inhibitor GRL-8234 in 5XFAD Alzheimer's transgenic mice lessen during disease progression.
Curr Alzheimer Res
; 12(1): 13-21, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25523425
12.
Selective neurodegeneration of hippocampus and entorhinal cortex correlates with spatial learning impairments in rats with bilateral ibotenate lesions of ventral subiculum.
Brain Res
; 960(1-2): 9-15, 2003 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-12505652
13.
PERK mediates eIF2α phosphorylation responsible for BACE1 elevation, CREB dysfunction and neurodegeneration in a mouse model of Alzheimer's disease.
Neurobiol Aging
; 35(10): 2272-81, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24889041
14.
Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease.
PLoS One
; 8(10): e77335, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24146979
15.
7,8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease.
Neuropsychopharmacology
; 37(2): 434-44, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21900882
16.
Mechanisms underlying insulin deficiency-induced acceleration of ß-amyloidosis in a mouse model of Alzheimer's disease.
PLoS One
; 7(3): e32792, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22403710
17.
Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice.
PLoS One
; 5(9): e12974, 2010 Sep 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-20886088
18.
Sex- and brain region-specific acceleration of ß-amyloidogenesis following behavioral stress in a mouse model of Alzheimer's disease.
Mol Brain
; 3: 34, 2010 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-21059265
19.
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.
J Biol Chem
; 283(14): 9089-100, 2008 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-18245082
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