Detalles de la búsqueda
1.
CaMKK2 is inactivated by cAMP-PKA signaling and 14-3-3 adaptor proteins.
J Biol Chem
; 295(48): 16239-16250, 2020 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-32913128
2.
The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling.
Immunol Rev
; 250(1): 277-302, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23046136
3.
The ßc receptor family - Structural insights and their functional implications.
Cytokine
; 74(2): 247-58, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25982846
4.
Distinct Assemblies of Heterodimeric Cytokine Receptors Govern Stemness Programs in Leukemia.
Cancer Discov
; 13(8): 1922-1947, 2023 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37191437
5.
Structure of rat aldose reductase-like protein AKR1B14 holoenzyme: Probing the role of His269 in coenzyme binding by site-directed mutagenesis.
Bioorg Med Chem Lett
; 21(2): 801-4, 2011 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21168333
6.
Probing the inhibitor selectivity pocket of human 20α-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis.
Bioorg Med Chem Lett
; 21(8): 2564-7, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21414777
7.
Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.
Acta Crystallogr D Biol Crystallogr
; 66(Pt 2): 198-204, 2010 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-20124700
8.
Factorizing the role of a critical leucine residue in the binding of substrate to human 20alpha-hydroxysteroid dehydrogenase (AKR1C1): molecular modeling and kinetic studies of the Leu308Val mutant enzyme.
Bioorg Med Chem Lett
; 20(17): 5274-6, 2010 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20656485
9.
Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.
Acta Crystallogr D Biol Crystallogr
; 65(Pt 3): 257-65, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19237748
10.
Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all-trans-retinal of a short-chain dehydrogenase/reductase (DHRS4).
Arch Biochem Biophys
; 481(2): 183-90, 2009 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19056333
11.
Author Correction: EPO does not promote interaction between the erythropoietin and beta-common receptors.
Sci Rep
; 9(1): 7851, 2019 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31110193
12.
Inhibition of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) by aldose reductase inhibitors.
Bioorg Med Chem
; 16(6): 3245-54, 2008 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18165015
13.
EPO does not promote interaction between the erythropoietin and beta-common receptors.
Sci Rep
; 8(1): 12457, 2018 08 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30127368
14.
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities.
MAbs
; 10(7): 1018-1029, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29969365
15.
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling.
Nat Commun
; 9(1): 386, 2018 01 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29374162
16.
Role of the ß Common (ßc) Family of Cytokines in Health and Disease.
Cold Spring Harb Perspect Biol
; 10(6)2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28716883
17.
Structure of 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: an insight into the bifunctionality of the enzyme.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 63(Pt 10): 825-30, 2007 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-17909281
18.
A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20alpha-hydroxysteroid dehydrogenase.
Med Chem
; 3(6): 546-50, 2007 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18045204
19.
Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling.
Structure
; 24(8): 1271-1281, 2016 08 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27396825
20.
CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common ß chain of the IL-3, GM-CSF and IL-5 receptors.
MAbs
; 8(3): 436-53, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26651396