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1.
Model-Informed Selection of the Recommended Phase III Dose of the Inhibitor of Apoptosis Protein Inhibitor, Xevinapant, in Combination with Cisplatin and Concurrent Radiotherapy in Patients with Locally Advanced Squamous Cell Carcinoma of the Head and Neck.
Clin Pharmacol Ther
; 115(1): 52-61, 2024 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37777832
2.
Predicted heart rate effect of inhaled PF-00610355, a long acting ß-adrenoceptor agonist, in volunteers and patients with chronic obstructive pulmonary disease.
Br J Clin Pharmacol
; 76(5): 752-62, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23323609
3.
Population Pharmacokinetics of Mivavotinib (TAK-659), a Dual Spleen Tyrosine Kinase and FMS-Like Tyrosine Kinase 3 Inhibitor, in Patients With Advanced Solid Tumors or Hematologic Malignancies.
J Clin Pharmacol
; 63(3): 326-337, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36309821
4.
Assessment of Effects of Investigational TAK-931, an Oral Cell Division Cycle 7 Kinase Inhibitor on the QTc Intervals in Patients With Advanced Solid Tumors.
Clin Pharmacol Drug Dev
; 11(6): 770-779, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35187855
5.
Population Pharmacokinetics of TAK-931, a Cell Division Cycle 7 Kinase Inhibitor, in Patients With Advanced Solid Tumors.
J Clin Pharmacol
; 62(3): 422-433, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34564871
6.
Population Pharmacokinetic and Pharmacodynamic Analysis of GLPG1690, an Autotaxin Inhibitor, in Healthy Volunteers and Patients with Idiopathic Pulmonary Fibrosis.
Clin Pharmacokinet
; 58(9): 1175-1191, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-30953319
7.
Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Modeling of Filgotinib (GLPG0634), a Selective JAK1 Inhibitor, in Support of Phase IIB Dose Selection.
Clin Pharmacokinet
; 54(8): 859-74, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25681059
8.
Characterizing systemic exposure of inhaled drugs: application to the long-acting ß2-agonist PF-00610355.
Clin Pharmacokinet
; 52(6): 443-52, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23494982
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