Detalles de la búsqueda
1.
Efficacy and safety of an interleukin 6 monoclonal antibody for the treatment of systemic lupus erythematosus: a phase II dose-ranging randomised controlled trial.
Ann Rheum Dis
; 76(3): 534-542, 2017 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-27672124
2.
Tofacitinib pharmacokinetics in children and adolescents with juvenile idiopathic arthritis.
CPT Pharmacometrics Syst Pharmacol
; 13(4): 599-611, 2024 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38298058
3.
Analysis of Disease Activity Metrics in a Methotrexate Withdrawal Study among Patients with Rheumatoid Arthritis Treated with Tofacitinib plus Methotrexate.
Rheumatol Ther
; 10(2): 375-386, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36534208
4.
Influenza Adverse Events in Patients with Rheumatoid Arthritis, Ulcerative Colitis, or Psoriatic Arthritis in the Tofacitinib Clinical Development Programs.
Rheumatol Ther
; 10(2): 357-373, 2023 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-36526796
5.
Evaluation of the Effect of Abrocitinib on Drug Transporters by Integrated Use of Probe Drugs and Endogenous Biomarkers.
Clin Pharmacol Ther
; 112(3): 665-675, 2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35344588
6.
Efficacy and safety of tofacitinib modified-release 11 mg once daily plus methotrexate in adult patients with rheumatoid arthritis: 24-week open-label phase results from a phase 3b/4 methotrexate withdrawal non-inferiority study (ORAL Shift).
RMD Open
; 7(2)2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34103405
7.
Associations between Patient Global Assessment scores and pain, physical function, and fatigue in rheumatoid arthritis: a post hoc analysis of data from phase 3 trials of tofacitinib.
Arthritis Res Ther
; 22(1): 243, 2020 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33059710
8.
Variability in Antinuclear Antibody Testing to Assess Patient Eligibility for Clinical Trials of Novel Treatments for Systemic Lupus Erythematosus.
Arthritis Rheumatol
; 71(9): 1534-1538, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31385442
9.
Methotrexate withdrawal in patients with rheumatoid arthritis who achieve low disease activity with tofacitinib modified-release 11 mg once daily plus methotrexate (ORAL Shift): a randomised, phase 3b/4, non-inferiority trial.
Lancet Rheumatol
; 1(1): e23-e34, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-38229356
10.
The oxidized subunit B8 from human complex I adopts a thioredoxin fold.
Structure
; 12(9): 1645-54, 2004 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-15341729
11.
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of SBI-087, a CD20-Directed B-cell Depleting Agent: Phase 1 Dose Escalating Studies in Patients With Either Mild Rheumatoid Arthritis or Systemic Lupus.
Clin Ther
; 38(6): 1417-1434.e2, 2016 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-27112532
12.
Safety and Efficacy of SBI-087, a Subcutaneous Agent for B Cell Depletion, in Patients with Active Rheumatoid Arthritis: Results from a Phase II Randomized, Double-blind, Placebo-controlled Study.
J Rheumatol
; 43(12): 2094-2100, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27909139
13.
The solution structure of the SODD BAG domain reveals additional electrostatic interactions in the HSP70 complexes of SODD subfamily BAG domains.
FEBS Lett
; 558(1-3): 101-6, 2004 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-14759524
14.
Reassessment of tigecycline bone concentrations in volunteers undergoing elective orthopedic procedures.
J Clin Pharmacol
; 54(1): 70-4, 2014 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24155157
15.
Comparative Sirolimus Pharmacokinetics After Single-Dose Administration of Two Prototype 0.5-mg Tablets in Healthy Volunteers.
Clin Pharmacol Drug Dev
; 1(2): 52-6, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-27121219
16.
Discovery of low-molecular-weight ligands for the AF6 PDZ domain.
Angew Chem Int Ed Engl
; 45(23): 3790-5, 2006 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-16671149
17.
The structure of MESD45-184 brings light into the mechanism of LDLR family folding.
Structure
; 19(3): 337-48, 2011 Mar 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-21397185
18.
Backbone and sidechain 1H, 13C and 15N resonance assignments of the RGS domain from human RGS14.
Biomol NMR Assign
; 1(1): 95-7, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19636837
19.
The solution structure of the core of mesoderm development (MESD), a chaperone for members of the LDLR-family.
J Struct Funct Genomics
; 7(3-4): 131-8, 2006 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17342452
20.
Measurement of multiple psi torsion angles in uniformly 13C,15N-labeled alpha-spectrin SH3 domain using 3D 15N-13C-13C-15N MAS dipolar-chemical shift correlation spectroscopy.
J Am Chem Soc
; 125(22): 6827-33, 2003 Jun 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-12769594