Detalles de la búsqueda
1.
Antivirulence Bispecific Monoclonal Antibody-Mediated Protection against Pseudomonas aeruginosa Ventilator-Associated Pneumonia in a Rabbit Model.
Antimicrob Agents Chemother
; 66(2): e0202221, 2022 02 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34902264
2.
Multimechanistic Monoclonal Antibody Combination Targeting Key Staphylococcus aureus Virulence Determinants in a Rabbit Model of Prosthetic Joint Infection.
Antimicrob Agents Chemother
; 65(7): e0183220, 2021 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33903108
3.
Pseudomonas aeruginosa Ventilator-Associated Pneumonia Rabbit Model for Preclinical Drug Development.
Antimicrob Agents Chemother
; 65(7): e0272420, 2021 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-33972247
4.
Efficacy of Active Immunization With Attenuated α-Hemolysin and Panton-Valentine Leukocidin in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.
J Infect Dis
; 221(2): 267-275, 2020 01 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31504652
5.
Protective Efficacy of Monoclonal Antibodies Neutralizing Alpha-Hemolysin and Bicomponent Leukocidins in a Rabbit Model of Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 64(3)2020 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-31844012
6.
FDA Public Workshop Summary: Advancing Animal Models for Antibacterial Drug Development.
Antimicrob Agents Chemother
; 65(1)2020 12 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-33106262
7.
Necrotizing Soft Tissue Infection Staphylococcus aureus but not S. pyogenes Isolates Display High Rates of Internalization and Cytotoxicity Toward Human Myoblasts.
J Infect Dis
; 220(4): 710-719, 2019 07 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31001627
8.
Treatment Efficacy of MEDI3902 in Pseudomonas aeruginosa Bloodstream Infection and Acute Pneumonia Rabbit Models.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31160288
9.
The Role of Antibiotics in Modulating Virulence in Staphylococcus aureus.
Clin Microbiol Rev
; 30(4): 887-917, 2017 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-28724662
10.
MEDI3902 Correlates of Protection against Severe Pseudomonas aeruginosa Pneumonia in a Rabbit Acute Pneumonia Model.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29483116
11.
Effects of Tedizolid Phosphate on Survival Outcomes and Suppression of Production of Staphylococcal Toxins in a Rabbit Model of Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28137816
12.
Targeting Alpha Toxin To Mitigate Its Lethal Toxicity in Ferret and Rabbit Models of Staphylococcus aureus Necrotizing Pneumonia.
Antimicrob Agents Chemother
; 61(4)2017 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28115346
13.
Improved Protection in a Rabbit Model of Community-Associated Methicillin-Resistant Staphylococcus aureus Necrotizing Pneumonia upon Neutralization of Leukocidins in Addition to Alpha-Hemolysin.
Antimicrob Agents Chemother
; 60(10): 6333-40, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27527081
14.
Critical Role of Alpha-Toxin and Protective Effects of Its Neutralization by a Human Antibody in Acute Bacterial Skin and Skin Structure Infections.
Antimicrob Agents Chemother
; 60(10): 5640-8, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27401576
15.
Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.
PLoS Pathog
; 9(10): e1003653, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-24130480
16.
Identifying potential therapeutic targets of methicillin-resistant Staphylococcus aureus through in vivo proteomic analysis.
J Infect Dis
; 209(10): 1533-41, 2014 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24280367
17.
Global gene expression of methicillin-resistant Staphylococcus aureus USA300 during human and mouse infection.
J Infect Dis
; 209(10): 1542-50, 2014 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24286981
18.
Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus necrotizing pneumonia.
J Infect Dis
; 208(1): 75-82, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23532096
19.
Clonal composition and community clustering of drug-susceptible and -resistant Escherichia coli isolates from bloodstream infections.
Antimicrob Agents Chemother
; 57(1): 490-7, 2013 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-23147723
20.
Cross-talk between Staphylococcus aureus leukocidins-intoxicated macrophages and lung epithelial cells triggers chemokine secretion in an inflammasome-dependent manner.
Cell Microbiol
; 14(7): 1019-36, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22329718