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1.
MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status.
Acta Neuropathol
; 124(4): 547-60, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-22810491
2.
Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial.
Acta Neuropathol
; 123(6): 841-52, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22249618
3.
Anti-O6-methylguanine-methyltransferase (MGMT) immunohistochemistry in glioblastoma multiforme: observer variability and lack of association with patient survival impede its use as clinical biomarker.
Brain Pathol
; 18(4): 520-32, 2008 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-18400046
4.
Infrequent promoter methylation of the MGMT gene in liver metastases from uveal melanoma.
Int J Cancer
; 123(5): 1215-8, 2008 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18546261
5.
MGMT gene silencing and benefit from temozolomide in glioblastoma.
N Engl J Med
; 352(10): 997-1003, 2005 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-15758010
6.
Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma.
J Mol Diagn
; 10(4): 332-7, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18556773
7.
Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes.
Cancer Res
; 63(20): 6613-25, 2003 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14583454
8.
INK4a/Arf is required for suppression of EGFR/DeltaEGFR(2-7)-dependent ERK activation in mouse astrocytes and glioma.
Oncogene
; 23(41): 6854-63, 2004 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-15273738
9.
Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide.
Clin Cancer Res
; 10(6): 1871-4, 2004 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-15041700
10.
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro Oncol
; 14(6): 701-11, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22570425
11.
The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence.
Neuro Oncol
; 13(7): 736-47, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21642372
12.
Extent and patterns of MGMT promoter methylation in glioblastoma- and respective glioblastoma-derived spheres.
Clin Cancer Res
; 17(2): 255-66, 2011 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21097691
13.
Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib--a phase II trial.
Mol Cancer Ther
; 10(6): 1102-12, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21471286
14.
Phase I/IIa study of cilengitide and temozolomide with concomitant radiotherapy followed by cilengitide and temozolomide maintenance therapy in patients with newly diagnosed glioblastoma.
J Clin Oncol
; 28(16): 2712-8, 2010 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20439646
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