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1.
From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.
Bioorg Med Chem Lett
; 22(8): 2963-7, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22386529
2.
Identification of a novel series of BET family bromodomain inhibitors: binding mode and profile of I-BET151 (GSK1210151A).
Bioorg Med Chem Lett
; 22(8): 2968-72, 2012 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22437115
3.
Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase.
J Med Chem
; 62(10): 5096-5110, 2019 05 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-31013427
4.
Design and evaluation of a novel series of 2,3-oxidosqualene cyclase inhibitors with low systemic exposure, relationship between pharmacokinetic properties and ocular toxicity.
Bioorg Med Chem
; 16(11): 6218-32, 2008 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18467104
5.
Substituted 2-[(4-aminomethyl)phenoxy]-2-methylpropionic acid PPARalpha agonists. 1. Discovery of a novel series of potent HDLc raising agents.
J Med Chem
; 50(4): 685-95, 2007 Feb 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-17243659
6.
Discovery of Pyridones As Oral AMPK Direct Activators.
ACS Med Chem Lett
; 4(7): 632-6, 2013 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900722
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