Detalles de la búsqueda
1.
Stricturing Crohn's Disease Single-Cell RNA Sequencing Reveals Fibroblast Heterogeneity and Intercellular Interactions.
Gastroenterology
; 165(5): 1180-1196, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37507073
2.
41-Week Study of Progressive Diabetic Nephropathy in the ZSF1 fa/faCP Rat Model.
Toxicol Pathol
; 46(8): 976-977, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30278832
3.
Efficacy and Pharmacology of the NLRP3 Inflammasome Inhibitor CP-456,773 (CRID3) in Murine Models of Dermal and Pulmonary Inflammation.
J Immunol
; 197(6): 2421-33, 2016 09 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27521339
4.
The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection.
PLoS Pathog
; 10(2): e1003904, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-24516381
5.
Interleukin 1/Toll-like receptor-induced autophosphorylation activates interleukin 1 receptor-associated kinase 4 and controls cytokine induction in a cell type-specific manner.
J Biol Chem
; 289(15): 10865-10875, 2014 Apr 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-24567333
6.
Myxoma and vaccinia viruses bind differentially to human leukocytes.
J Virol
; 87(8): 4445-60, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23388707
7.
Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library.
J Virol
; 86(5): 2632-40, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22205744
8.
A protein kinase C α and ß inhibitor blunts hyperphagia to halt renal function decline and reduces adiposity in a rat model of obesity-driven type 2 diabetes.
Sci Rep
; 13(1): 16919, 2023 10 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37805649
9.
Identification of a broadly fibrogenic macrophage subset induced by type 3 inflammation.
Sci Immunol
; 8(82): eadd8945, 2023 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-37027478
10.
Stricturing Crohn's disease single-cell RNA sequencing reveals fibroblast heterogeneity and intercellular interactions.
bioRxiv
; 2023 Apr 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-37066202
11.
The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial.
Arthritis Rheumatol
; 73(12): 2206-2218, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34423919
12.
TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines.
Rheumatology (Oxford)
; 48(11): 1352-8, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19713442
13.
Computational identification and validation of alternative splicing in ZSF1 rat RNA-seq data, a preclinical model for type 2 diabetic nephropathy.
Sci Rep
; 8(1): 7624, 2018 05 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-29769602
14.
Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation.
Mol Cell Biol
; 22(23): 8254-66, 2002 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-12417728
15.
High resolution molecular and histological analysis of renal disease progression in ZSF1 fa/faCP rats, a model of type 2 diabetic nephropathy.
PLoS One
; 12(7): e0181861, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28746409
16.
Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.
PLoS One
; 12(9): e0184843, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28934246
17.
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
J Med Chem
; 60(13): 5521-5542, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28498658
18.
Probing the virus host interaction in high containment: an approach using pooled short hairpin RNA.
Assay Drug Dev Technol
; 13(1): 34-43, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25646658
19.
Vaccinia reporter viruses for quantifying viral function at all stages of gene expression.
J Vis Exp
; (87)2014 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24894622
20.
Stimulation of TLR4 by recombinant HSP70 requires structural integrity of the HSP70 protein itself.
J Inflamm (Lond)
; 9: 11, 2012 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22448747