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1.
Successful application of serum shift prediction models to the design of dual targeting inhibitors of bacterial gyrase B and topoisomerase IV with improved in vivo efficacy.
Bioorg Med Chem Lett
; 24(9): 2177-81, 2014 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-24685546
2.
Identification and evaluation of novel acetolactate synthase inhibitors as antifungal agents.
Antimicrob Agents Chemother
; 57(5): 2272-80, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23478965
3.
Optimization of CoaD Inhibitors against Gram-Negative Organisms through Targeted Metabolomics.
ACS Infect Dis
; 4(3): 391-402, 2018 03 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29243909
4.
Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase from Gram-Negative Bacteria.
J Med Chem
; 61(8): 3309-3324, 2018 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29498517
5.
Discovery and Optimization of Phosphopantetheine Adenylyltransferase Inhibitors with Gram-Negative Antibacterial Activity.
J Med Chem
; 61(8): 3325-3349, 2018 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-29551072
6.
Novel dual-targeting benzimidazole urea inhibitors of DNA gyrase and topoisomerase IV possessing potent antibacterial activity: intelligent design and evolution through the judicious use of structure-guided design and structure-activity relationships.
J Med Chem
; 51(17): 5243-63, 2008 Sep 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-18690678
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