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1.
Effect of lipophilicity on drug distribution and elimination: Influence of obesity.
Br J Clin Pharmacol
; 87(8): 3197-3205, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-33450083
2.
Race, Gender, and Genetic Polymorphism Contribute to Variability in Acetaminophen Pharmacokinetics, Metabolism, and Protein-Adduct Concentrations in Healthy African-American and European-American Volunteers.
J Pharmacol Exp Ther
; 362(3): 431-440, 2017 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-28663312
3.
The UDP-glucuronosyltransferase (UGT) 1A polymorphism c.2042C>G (rs8330) is associated with increased human liver acetaminophen glucuronidation, increased UGT1A exon 5a/5b splice variant mRNA ratio, and decreased risk of unintentional acetaminophen-induced acute liver failure.
J Pharmacol Exp Ther
; 345(2): 297-307, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23408116
4.
Mechanism of cytochrome P450-3A inhibition by ketoconazole.
J Pharm Pharmacol
; 63(2): 214-21, 2011 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-21235585
5.
Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and Cyp2e1(-/-) mice.
Drug Metab Dispos
; 35(7): 1223-31, 2007 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-17392391
6.
Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.
Drug Metab Dispos
; 33(6): 764-70, 2005 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-15764714
7.
Synthesis and evaluation of hydrolyzable hyaluronan-tethered bupivacaine delivery systems.
Bioconjug Chem
; 16(6): 1512-8, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-16287249
8.
Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity.
Drug Metab Dispos
; 33(12): 1827-36, 2005 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-16141365
9.
Validation of serotonin (5-hydroxtryptamine) as an in vitro substrate probe for human UDP-glucuronosyltransferase (UGT) 1A6.
Drug Metab Dispos
; 31(1): 133-9, 2003 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-12485962
10.
Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.
Drug Metab Dispos
; 31(9): 1125-33, 2003 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12920168
11.
Stereoselective conjugation of oxazepam by human UDP-glucuronosyltransferases (UGTs): S-oxazepam is glucuronidated by UGT2B15, while R-oxazepam is glucuronidated by UGT2B7 and UGT1A9.
Drug Metab Dispos
; 30(11): 1257-65, 2002 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-12386133
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