Detalles de la búsqueda
1.
Cholesteryl ester transfer protein (CETP) inhibitors based on cyclic urea, bicyclic urea and bicyclic sulfamide cores.
Bioorg Med Chem Lett
; 32: 127668, 2021 01 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33161125
2.
Successful switching of patients with acute schizophrenia from another antipsychotic to brexpiprazole: comparison of clinicians' choice of cross-titration schedules in a post hoc analysis of a randomized, double-blind, maintenance treatment study.
CNS Spectr
; 24(5): 507-517, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30306884
3.
Agitation in patients with dementia: a systematic review of epidemiology and association with severity and course.
Int Psychogeriatr
; 31(9): 1305-1318, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-30855002
4.
An Integrated Pharmacokinetic-Pharmacodynamic-Pharmacoeconomic Modeling Method to Evaluate Treatments for Adults with Schizophrenia.
Pharmacoeconomics
; 40(1): 121-131, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34622429
5.
Making Sense of the Matrix: A Qualitative Assessment and Commentary on Connecting Psychiatric Symptom Scale Items to the Research Domain Criteria (RDoC).
Innov Clin Neurosci
; 19(1-3): 26-32, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35382070
6.
Diaryl piperidines as CB1 receptor antagonists.
Bioorg Med Chem Lett
; 20(3): 1278-83, 2010 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20018510
7.
Real-World Treatment Patterns and Characteristics Among Patients with Agitation and Dementia in the United States: Findings from a Large, Observational, Retrospective Chart Review.
J Alzheimers Dis
; 77(3): 1181-1194, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32925028
8.
Association of the US Food and Drug Administration Antipsychotic Drug Boxed Warning With Medication Use and Health Outcomes in Elderly Patients With Dementia.
JAMA Netw Open
; 3(4): e203630, 2020 04 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32343351
9.
Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model.
J Med Chem
; 51(8): 2439-46, 2008 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-18363352
10.
Discovery of a novel, potent and orally active series of gamma-lactams as selective NK1 antagonists.
Bioorg Med Chem Lett
; 18(14): 4168-71, 2008 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18547807
11.
The effects of brexpiprazole and aripiprazole on body weight as monotherapy in patients with schizophrenia and as adjunctive treatment in patients with major depressive disorder: an analysis of short-term and long-term studies.
Int Clin Psychopharmacol
; 33(5): 255-260, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29878915
12.
The Role of Norepinephrine and Its α-Adrenergic Receptors in the Pathophysiology and Treatment of Major Depressive Disorder and Schizophrenia: A Systematic Review.
Front Psychiatry
; 8: 42, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28367128
13.
Long-term outcomes of antipsychotic treatment in patients with first-episode schizophrenia: a systematic review.
Neuropsychiatr Dis Treat
; 12: 57-67, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26792993
14.
Hospital Readmission Rates Among Patients With Schizophrenia Treated With Long-Acting Injectables or Oral Antipsychotics.
Psychiatr Serv
; 67(11): 1183-1188, 2016 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27417897
15.
Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach.
ACS Med Chem Lett
; 7(3): 261-5, 2016 Mar 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-26985312
16.
The gerbil elevated plus-maze II: anxiolytic-like effects of selective neurokinin NK1 receptor antagonists.
Neuropsychopharmacology
; 27(3): 371-9, 2002 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-12225694
17.
Improving the oral efficacy of CNS drug candidates: discovery of highly orally efficacious piperidinyl piperidine M2 muscarinic receptor antagonists.
J Med Chem
; 45(25): 5415-8, 2002 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-12459007
18.
Potential therapeutic targets for neurokinin-1 receptor antagonists.
Expert Opin Emerg Drugs
; 9(1): 9-21, 2004 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15155133
19.
Rolapitant (SCH 619734): a potent, selective and orally active neurokinin NK1 receptor antagonist with centrally-mediated antiemetic effects in ferrets.
Pharmacol Biochem Behav
; 102(1): 95-100, 2012 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-22497992
20.
Cyclobutane derivatives as potent NK1 selective antagonists.
Bioorg Med Chem Lett
; 16(14): 3859-63, 2006 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16682196