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1.
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD.
Neurobiol Dis
; 179: 106050, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36809847
2.
Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.
Arch Toxicol
; 95(10): 3341-3359, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34313809
3.
Cytostatic Effect of Repeated Exposure to Simvastatin: A Mechanism for Chronic Myotoxicity Revealed by the Use of Mesodermal Progenitors Derived from Human Pluripotent Stem Cells.
Stem Cells
; 33(10): 2936-48, 2015 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26184566
4.
Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.
MAbs
; 15(1): 2232087, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37408314
5.
Targeting amyotrophic lateral sclerosis by neutralizing seeding-competent TDP-43 in CSF.
Brain Commun
; 5(6): fcad306, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38025276
6.
Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Nat Commun
; 11(1): 4110, 2020 08 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32807790
7.
Substrate Topography Modulates Cell Aging on a Progeria Cell Model.
ACS Biomater Sci Eng
; 4(5): 1498-1504, 2018 May 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-33445307
8.
Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford Progeria Syndrome (HGPS) revealed an impaired melanogenesis pathway in iPS-derived melanocytes.
Sci Rep
; 8(1): 9112, 2018 06 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-29904107
9.
A High Throughput Phenotypic Screening reveals compounds that counteract premature osteogenic differentiation of HGPS iPS-derived mesenchymal stem cells.
Sci Rep
; 6: 34798, 2016 10 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-27739443
10.
Metformin decreases progerin expression and alleviates pathological defects of Hutchinson-Gilford progeria syndrome cells.
NPJ Aging Mech Dis
; 2: 16026, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-28721276
11.
Induced pluripotent stem cells reveal functional differences between drugs currently investigated in patients with hutchinson-gilford progeria syndrome.
Stem Cells Transl Med
; 3(4): 510-9, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24598781
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